MEDICATION UTILIZATION AND STATIN ADHERENCE IN THE MANAGEMENT OF DYSLIPIDEMIA AT THONG NHAT HOSPITAL, HO CHI MINH CITY, 2016-2023

Nguyễn Thanh Huy 1 , Lê Hoàng Minh Tâm 1 , Trần Ngọc Thiên Phú 1 , Quang Ánh Nguyệt 1 , Phạm Thị Thu Hiền 2 , Phạm Đình Luyến 1 ,
1 University of Medicine and Pharmacy at Ho Chi Minh City image/svg+xml
2 Thong Nhat Hospital image/svg+xml
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DOI
10.63947/bvtn.v2i6.12
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Published
2026-02-27
Issue Vol. 2 No. 6 (2026): Thách thức trong lão khoa 2026: Những giải pháp điều trị và chăm sóc toàn diện
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Original Research

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Huy NT, Tâm LHM, Phú TNT, Nguyệt QÁ, Hiền PTT, Luyến PĐ. MEDICATION UTILIZATION AND STATIN ADHERENCE IN THE MANAGEMENT OF DYSLIPIDEMIA AT THONG NHAT HOSPITAL, HO CHI MINH CITY, 2016-2023. JHA [Internet]. Vietnam; 2026 Feb. 27 [cited 2026 Sep. 16];2(6). https://tcsuckhoelaohoa.vn/bvtn/article/view/162 doi: 10.63947/bvtn.v2i6.12
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Abstract

Dyslipidemia (DLP) is a major risk factor for cardiovascular disease, and statins are the first-line treatment. The level of adherence to statin treatment has a significant impact on treatment outcomes in patients. This study aims to evaluate the medication utilization patterns and statin adherence levels at Thong Nhat Hospital during the 2016-2023 period. A retrospective cross-sectional study was conducted on 23,373 outpatients with dyslipidemia (ICD-10: E78) who had a continuous treatment duration of ≥1 year. Demographic characteristics, comorbidities (CCI), and prescription information were analyzed; statin adherence levels were assessed using MPR and PDC, with the threshold for good adherence being MPR >80% và PDC ≥80%. The mean age was 66,1 ± 12,2 with 72% of patients aged ≥ 60 years and a high multimorbidity burden (mean CCI of 5.91). Among 461,435 examination visits with prescribed treatment, statins accounted for 96.4%, primarily rosuvastatin and atorvastatin at moderate doses. The utilization rate of fixed-dose combinations (FDC) increased from 10.1% (2016) to 25.5% (2023). Adherence levels were low, with a mean MPR of 0.33 and PDC of 0.30; only 5.64% of patients achieved MPR > 80% and 3.53% achieved PDC ≥80%. The study indicates that statins are primarily used in dyslipidemia treatment with a growing trend toward FDC usage; however, the level of treatment adherence remains low.

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References

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