THE VALUE OF THE MODIFIED GLASGOW BLATCHFORD SCORE IN PREDICTING OUTCOMES IN NON-VARICEAL UPPER GASTROINTESTINAL BLEEDING

Phạm Hoàng Thiên 1 , , Đỗ Thị Hồng Ngọc 1 , Dương Thị Kim Ngân 1 , Nguyễn Thị Thành 1
1 Thong Nhat Hospital
* Corresponding author:

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A 50-Year Journey in Establishing a Position and Promoting Sustainable Development in Healthcare and Geriatrics
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DOI
10.63947/bvtn.v1i1.17
Published
2025-06-03
Issue Vol. 1 No. 1 (2025): A 50-Year Journey in Establishing a Position and Promoting Sustainable Development in Healthcare and Geriatrics
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Original Paper

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Thiên PH, Ngọc Đỗ TH, Ngân DTK, Thành NT. THE VALUE OF THE MODIFIED GLASGOW BLATCHFORD SCORE IN PREDICTING OUTCOMES IN NON-VARICEAL UPPER GASTROINTESTINAL BLEEDING. JHA [Internet]. Vietnam; 2025 Jun. 3 [cited 2025 Jun. 23];1(1):110–114. https://tcsuckhoelaohoa.vn/bvtn/article/view/20 doi: 10.63947/bvtn.v1i1.17
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Abstract

Non-variceal upper gastrointestinal bleeding (UGIB) is a common medical and surgical emergency,  and risk stratification upon patient admission is of great importance. Therefore, evaluating the predictive value of the Modified Glasgow Blatchford Score (mGBS) compared to the Full Glasgow Blatchford Score (GBS) and the Clinical Rockall Score (CRS) in patients with non-variceal UGIB upon hospital admission is essential. This study aimed to assess the value of the mGBS in predicting outcomes in non-variceal UGIB due to portal hypertension. A prospective cohort study was conducted on patients with non-variceal UGIB due to portal hypertension admitted to the Department of Gastroenterology, Thong Nhat Hospital, from January 2024 to July 2024. The mGBS, GBS, and CRS were calculated, and the area under the receiver operating characteristic curve (AUC) was compared to determine the predictive performance of these scores for interventions including blood transfusion, endoscopic hemostasis, and overall medical intervention. A total of 130 eligible patients with non-variceal UGIB due to portal hypertension were included. The mean age was 57.5 ± 19.8 years, with a male-to-female ratio of 3.1:1. The in-hospital rebleeding rate was 5.4%. Medical interventions were required in 59.2% of cases, including blood transfusion in 45.4%, endoscopic intervention in 28.5%, and surgery in 3.1%. In terms of predicting the need for medical intervention, the mGBS (AUC = 0.845) performed similarly to the GBS (AUC = 0.844; p = 0.37) and outperformed the CRS (AUC = 0.707; p < 0.001). The Modified Glasgow Blatchford Score demonstrated good predictive value for medical intervention in patients with non-variceal UGIB due to portal hypertension and may be widely applicable in clinical practice.

Keywords

Non-variceal upper gastrointestinal bleeding Modified Glasgow Blatchford Score Full Glasgow Blatchford Score Clinical Rockall Score medical intervention in-hospital mortality in-hospital rebleeding

References

  1. Blatchford O., Murray O.R., Blatchford M. A risk score to predict need for treatment for uppergastrointestinal haemorrhage". The Lancet; 2000; 356 (9238); pp. 1318-1321.
  2. Cheng D.W., Lu Y.W., Teller T., et al. A modified Glasgow Blatchford Score improves risk stratification in upper gastrointestinal bleed: a prospective comparison of scoring systems. Aliment Pharmacol Ther; 2012; 36:782-789.
  3. Quách Trọng Đức, Đào Hữu Ngôi, Đinh Cao Minh và cộng sự. Giá trị của thang điểm Blatchford sửa đổi trong xuất huyết tiêu hoá trên cấp không do tăng áp lực tĩnh mạchc cửa: Kết quả nghiên cứu đoàn hệ tiến cứu đa trung tâm. Tạp chí y học TP Hồ Chí Minh, 2015, 19(1), tr 263-268.
  4. Robert V. Bryant, Paul Kuo, Kate Williamson, Chantelle Yam, et al. Performance of the Glasgow-Blatchford score in predicting clinical outcomes and intervention in hospitalized patients with upper GI bleeding, Gastrointest Endosc. 2013;78(4):576-83.
  5. Rockall TA, Logan RF,Devlin HB, et al. Risk assessment after acute upper gastrointestinal haemorrhage. Gut;1996; 38, pp 316-21.
  6. Trần Kinh Thành, Bùi Hữu Hoàng. Thang điểm Rockall và Blatchford trong đánh giá tiên lượng ở bệnh nhân xuất huyết tiêu hóa do loét dạ dày – tá tràng. Y học TP. Hồ Chí Minh; 2011; 15, tr 63-70.
  7. Van Leerdam M.E. , Vreeburg E.M. , Rauws E.A. , et al. Acute upper GI bleeding: did anything change? Time trend analysis of incidence and outcome of acute upper GI bleeding between 1993/1994 and 2000Am J Gastroenterol, 98 (2003), pp. 1494-1499.

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