Prevalence and associated factors of protein-energy wasting syndrome in chronic kidney disease patients on maintenance hemodialysis

Nguyễn Cảnh Hiền 1, 2 , Nguyễn Hoàng Phú 3 , , Ngô Văn Truyền 1 , Phan Hữu Hên 1
1 Can Tho University of Medicine and Pharmacy image/svg+xml
2 Ninh Thuan General Hospital, Khanh Hoa, Vietnam
3 Thong Nhat Hospital image/svg+xml
* Corresponding author:

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DOI
10.63947/bvtn.v2i9.8
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Published
2026-10-01
Issue Vol. 2 No. 9 (2026): A Major Step Forward in Specialized Care: A Milestone Marked by the First Liver Transplant at Thong Nhat Hospital
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Original Research

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Nguyễn CH, Nguyễn HP, Ngô VT, Phan HH. Prevalence and associated factors of protein-energy wasting syndrome in chronic kidney disease patients on maintenance hemodialysis. JHA [Internet]. Vietnam; 2026 Oct. 1 [cited 2026 Oct. 16];2(9):61–66. https://tcsuckhoelaohoa.vn/bvtn/article/view/225 doi: 10.63947/bvtn.v2i9.8
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Abstract

To determine the prevalence and analyze the associated factors of protein-energy wasting (PEW) syndrome in chronic kidney disease patients on maintenance hemodialysis. A cross-sectional descriptive study. Study location and duration: Department of Nephrology, Ninh Thuan General Hospital from June 2025 to June 2026. Study subjects: 166 patients (>18 years old) with end-stage renal disease undergoing stable maintenance hemodialysis. The prevalence of patients with PEW syndrome is 24.1%. The most common constituent criteria are prominent signs of anorexia (57.8%), decreased mid-arm circumference (36.7%), and decreased serum albumin (36.1%). Associated factor analysis shows that male gender is a protective factor against PEW (OR = 0.167; p = 0.001), meaning females have a higher risk of the disease. The hemoglobin concentration in the PEW group is lower than that of the non-PEW group (8.2 compared to 9.0 g/dL; p = 0.010). The prevalence of PEW syndrome in maintenance hemodialysis patients is 24.1%. Female gender and anemia are associated factors, which require early monitoring and nutritional intervention.

Keywords

Protein-energy wasting hemodialysis chronic kidney disease

References

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