SURVEY ON THE CORRELATION OF TRIGLYCERIDE AND LIPASE, CRP, LEUKOCYTE INDICATORS IN PATIENTS WITH ACUTE PANCREATITIS HOSPITALIZED AT THONG NHAT HOSPITAL

Cao Thị Vân 1 , , Đỗ Thị Phương 1 , Hồ Thị Ngọc Hạnh 1 , Lê Thị Kim Cương , Võ Trung Đình 1 , Nguyễn Hữu Nghị 1
1 Thong Nhat Hospital
* Corresponding author:

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DOI
10.63947/bvtn.v1i2.12
Published
2025-06-15
Issue Vol. 1 No. 2 (2025): Aging Population and Healthcare Challenges
Section
Original Paper
Categories
Research

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1.
Thị Vân C, Thị Phương Đỗ, Thị Ngọc Hạnh H, Thị Kim Cương L, Trung Đình V, Hữu Nghị N. SURVEY ON THE CORRELATION OF TRIGLYCERIDE AND LIPASE, CRP, LEUKOCYTE INDICATORS IN PATIENTS WITH ACUTE PANCREATITIS HOSPITALIZED AT THONG NHAT HOSPITAL. JHA [Internet]. Vietnam; 2025 Jun. 15 [cited 2025 Jun. 23];1(2):88–93. https://tcsuckhoelaohoa.vn/bvtn/article/view/43 doi: 10.63947/bvtn.v1i2.12
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Abstract

To investigate the correlation between triglyceride, lipase, C-reactive protein (CRP), and white blood cell (WBC) levels in patients with acute pancreatitis (AP) upon hospital admission. A cross-sectional analytical study was conducted involving 222 patients admitted to Thong Nhat Hospital between January 2023 and March 2025. Data on triglyceride, lipase, CRP, WBC levels were collected at the time of admission. Among AP patients, 68% had elevated triglyceride levels. Specifically, 30% had moderately elevated triglycerides, while 28% had severely or very severely elevated levels. The distribution of study indicators was wide. A weak negative correlation was found between lipase - triglyceride levels, and between lipase and CRP levels (p < 0,001). No significant correlation was observed between lipase and WBC levels, or between WBC and triglyceride levels at the time of admission. At the time of admission, 28% of AP patients had severe or very severe hypertriglyceridemia. Lipase levels showed a weak negative correlation with triglyceride and CRP levels. These findings suggest that triglyceride levels may be a useful marker for assessing the severity of AP.

Keywords

Acute pancreatitis hypertriglyceridemia Lipase

References

  1. Tạ Thành Văn – Hóa sinh lâm sàng – Nhà xuất bản y học Hà nội 2013. Chuyển hóa Liporpotein. Trang 55 – 64.
  2. Adiamah A, Psaltis E, Crook M, et al. A systematic review of the epidemiology, pathophysiology and current management of hyperlipidaemic pancreatitis. Clin Nutr. 2018;37:1810–1822.
  3. Lin Gao, Weiqin Li. Hypertriglyceridemia and acute pancreatitis: clinical and basic research—a narrative review. Journal of Pancreatology (2024).
  4. Scherer J, Singh V, Pitchumoni C, et al. Issues in hypertriglyceridemic pancreatitis-an update. J Clin Gastroenterol 2014;48:195.
  5. Tsuang W, Navaneethan U, Ruiz L, et al. Hypertriglyceridemic pancreatitis: Presentation and management. Am J Gastroenterol 2009;104:984–91.
  6. Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis 2012: revision of the Atlanta classification and definitions by international consensus. Gut. Jan 2013;62(1):102-11.
  7. Havel RJ. Pathogenesis, differentiation and management of hypertriglyceridemia. Adv Intern Med 1969; 15: 117-154.
  8. Hướng dẫn sử dụng hóa chất xét nghiệm Lipase của hãng Beckman Coulter.

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