INVESTIGATION OF PROCALCITONIN LEVELS IN PATIENTS AFTER CARDIAC SURGERY

Danh Bình An 1 , , Nguyễn Thị Thảo 1 , Nguyễn Thị Hoàng Phước 1
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DOI
10.63947/bvtn.v1i3.8
Published
2025-07-10
Issue Vol. 1 No. 3 (2025): Adapting to the trend of population aging and an aged population
Section
Original Paper
Categories
Research

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1.
Bình An D, Thị Thảo N, Thị Hoàng Phước N. INVESTIGATION OF PROCALCITONIN LEVELS IN PATIENTS AFTER CARDIAC SURGERY. JHA [Internet]. Vietnam; 2025 Jul. 10 [cited 2025 Jul. 22];1(3):64–69. https://tcsuckhoelaohoa.vn/bvtn/article/view/63 doi: 10.63947/bvtn.v1i3.8
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Abstract

Cardiac surgery patients with elevated serum procalcitonin (PCT) levels are associated with postoperative complications. The use of extracorporeal circulation is linked to an increase in PCT levels within the first 24 hours after cardiac surgery. We conducted this study with the aim of investigating serum procalcitonin levels in patients after cardiac surgery. A cross-sectional, 52 cardiac surgery patients meeting the inclusion criteria for the study. The median serum PCT level was 3.2 pg/ml. The highest value was 175 pg/ml, and the lowest was 0.03 pg/ml. Serum procalcitonin levels between the group of cardiac surgery patients with and without the use of extracorporeal circulation were 20.7 (95% CI: 9.5-31.8) and 2.8 (0.03-5.7), respectively, p=0.15. The area under the ROC curve (AUC) of 0.42 indicates poor significance when relying on serum PCT to diagnose infection. Serum procalcitonin levels are elevated in patients after cardiac surgery. An elevated PCT value alone is not sufficient evidence to diagnose infection for clinical decision-making.

Keywords

Serum Procalcitonin Cardiac Surgery Extracorporeal Circulation Infection

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