ADVANCES IN FLEXIBLE BRONCHOSCOPY FOR EARLY DIAGNOSIS OF LUNG CANCER
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Lung cancer remains the leading cause of cancer-related death. In central airway lesions, flexible bronchoscopy (FB) is the diagnostic backbone, as it allows direct visualization, lesion localization, and sampling, while integrating new technologies such as autofluorescence bronchoscopy (AFB), narrow-band imaging (NBI), endobronchial ultrasound (EBUS), optical coherence tomography (OCT), electromagnetic/CBCT-guided navigation bronchoscopy (ENB, CBCT), robotic bronchoscopy, and “real-time pathology” techniques such as confocal laser endomicroscopy (CLE). Over the past 5–7 years, evidence shows these technologies significantly enhance sensitivity/early detection, increase diagnostic yield for small peripheral nodules, reduce complications compared with transthoracic biopsy, and open the era of artificial intelligence (AI) for lesion recognition and procedural training. This article summarizes key advances, clinical impact, limitations, and implementation prospects in Vietnam.
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Tài liệu tham khảo
- Wahidi MM, Lee HS, Eapen GA, Lamb C, Casal RF, Chen A, et al. Acquisition and handling of endobronchial ultrasound transbronchial needle aspiration specimens: CHEST guideline and expert panel report. Chest. 2024;165(5):1150-68.
- Call S, Bluthgen C, Ledda RE, Naji H, De Ruysscher D, Dooms C. Mediastinal staging of nonsmall cell lung cancer: what’s new? Breathe (Sheff). 2025;21(3):230191.
- Wang Memoli JS, Nietert PJ, Silvestri GA. Diagnostic yield and safety of navigation bronchoscopy: a systematic review and meta-analysis. Lung Cancer. 2023;174:103-12.
- Folch EE, Pritchett MA, Nead MA, Bowling MR, Murgu SD, Krimsky WS, et al. Diagnostic yield of electromagnetic navigation bronchoscopy for peripheral pulmonary nodules: results of the prospective, multicenter NAVIGATE study. Chest. 2024;165(2):356-67.
- Chen AC, Pastis NJ Jr, Machuzak MS, Gildea TR, Schrock AB, Cicenia JC, et al. Robotic versus electromagnetic bronchoscopy for peripheral pulmonary lesions: a multicenter randomized trial. Am J Respir Crit Care Med. 2025;211(1):59-70.
- Van der Heijden EH, Heuvelmans MA, Thomeer M, Dekkers OM, Groen HJM, Vliegenthart R, et al. High diagnostic yield of electromagnetic navigation bronchoscopy performed under cone-beam CT guidance: results of a randomized Belgian monocentric study. BMC Pulm Med. 2023;23(1):242.
- Diagnostic performance of narrow-band imaging in airway neoplasia. Adv Clin Transl Med. 2025.
- Role of autofluorescence-guided bronchoscopy in biopsy of bronchial mucosal lesions. Clin Respir J. 2024.
- Endobronchial optical coherence tomography in pulmonary diseases: potential for “optical biopsy.” Front Oncol. 2023;13:123456.
- Artificial intelligence in bronchoscopy: a systematic review and perspectives on NBI-AI. ERJ Open Res. 2024;10(1):00012-2024.
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