ASSESSING ANTIMICROBIAL THERAPY IN TREATING HEALTHCARE-ASSOCIATED INFECTIONS AT A VIETNAMESE NATIONAL HOSPITAL

Nguyen Ngoc Phuong Thanh 1 , Vo Trung Dinh 1 , Bui Thi Huong Quynh 1, 2 ,
1 Bệnh viện Thống Nhất image/svg+xml
2 Đại học Y Dược Thành phố Hồ Chí Minh image/svg+xml
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DOI
10.63947/bvtn.v2i7.8
Xuất bản
27-02-2026
Số Tập 2 Số 7 (2026): Multimodal approaches in geriatrics
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Ngoc Phuong Thanh N, Trung Dinh V, Thi Huong Quynh B. ASSESSING ANTIMICROBIAL THERAPY IN TREATING HEALTHCARE-ASSOCIATED INFECTIONS AT A VIETNAMESE NATIONAL HOSPITAL. JHA [Internet]. Vietnam; 2026 tháng 2 27 [cited 2026 tháng 2 28];2(7):58–72. https://tcsuckhoelaohoa.vn/bvtn/article/view/178 doi: 10.63947/bvtn.v2i7.8
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Tóm tắt

To evaluate the appropriateness of antimicrobial therapy in treating healthcare-associated infections and identify factors associated with patient outcomes at a national hospital in Vietnam. A cross-sectional study was conducted on 122 medical records of patients who were diagnosed with healthcare-associated infection at Thong Nhat Hospital from January 2023 to December 2023, using data from the Infection Control Department. Appropriateness of antimicrobial therapy was defined as physician adherence to Thong Nhat Hospital guidelines for antibiotic use. The factors associated with the treatment outcome were identified using multiple logistic regression analysis. The median age of the patients was 75.5 (65-85). Hospital-acquired pneumonia was identified in 51.6% of patients. The most prevalent pathogens were Klebsiella pneumoniae and Escherichia coli. The overall appropriate rate of empiric antimicrobial therapy was 76.2%. The successful treatment outcome rate was 71.3%. Lower respiratory tract infection, sepsis/sepsis shock, cancer, and comatose state were factors associated with treatment failure. Active management and treatment are essential for patients with lower respiratory infection, sepsis or septic shock, cancer, and comatose states to improve treatment outcomes.

Từ khóa

healthcare-associated infection antimicrobial therapy treatment outcome

Tài liệu tham khảo

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