CLINICAL AND LABORATORY CHARACTERISTICS AND EVALUATION OF CURB-65 IN RISK STRATIFICATION OF COMMUNITY ACQUIRED PNEUMONIA AT THONG NHAT HOSPITAL

Hoàng Thái Dương 1 , Hoàng Văn Quang 1 , Ngô Thế Hoàng 1 , , Nguyễn Duy Cường 1 , Nguyễn Thị Phương Thanh 1
1 Thong Nhat Hospital image/svg+xml
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2025-10-10
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1.
Thái Dương H, Văn Quang H, Thế Hoàng N, Duy Cường N, Thị Phương Thanh N. CLINICAL AND LABORATORY CHARACTERISTICS AND EVALUATION OF CURB-65 IN RISK STRATIFICATION OF COMMUNITY ACQUIRED PNEUMONIA AT THONG NHAT HOSPITAL. JHA [Internet]. Vietnam; 2025 Oct. 10 [cited 2025 Dec. 8];1(4):95–100. https://tcsuckhoelaohoa.vn/bvtn/article/view/119 doi: 10.63947/bvtn.v1i4.16
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Abstract

This study aimed to: (1) describe the clinical and paraclinical characteristics of patients with CAP; and (2) assess the prognostic value of the CURB-65 score in determining disease severity and predicting the need for hospitalization. A retrospective descriptive study was conducted on 250 adult patients diagnosed with CAP at Thong Nhat Hospital (Vietnam) between April 2023 and April 2025. Clinical symptoms, laboratory findings, chest radiography, and CURB-65 scores were collected and analyzed using SPSS 20.0. The correlation between CURB-65 and hospitalization was assessed using chi-square tests. The most common clinical symptoms were productive cough (74%), fever (67.6%), and dyspnea (54%). Radiographic abnormalities predominantly involved the right lung (43.6%). Elevated CRP (>5 mg/dL) and leukocytosis (>10,000 cells/mm³) were observed in 89.2% and 61.6% of patients, respectively. Among hospitalized patients, the majority had CURB- 65 scores ≥2 (p < 0.001). All patients with scores ≥4 were admitted to the ICU. CURB-65 is a simple and effective tool for initial risk stratification in patients with CAP. Its predictive value for hospitalization and intensive care admission supports its routine use in clinical practice, particularly in resource-limited settings.

Keywords

Community-acquired pneumonia CURB-65 risk stratification severity assessment hospitalization

References

  1. Bộ Y tế (2020). Hướng dẫn chẩn đoán và điều trị viêm phổi cộng đồng ở người lớn. QĐ 4815/QĐ-BYT.
  2. Nguyễn Thanh Hồi (2003). Tạp chí Y học Thực hành.
  3. Calis AG, Karaboga B, Uzer F, et al. (2025). Correlation of Pneumonia Severity Index and CURB-65 Score with NLR, PLR, and MLR in Predicting In-Hospital Mortality for CAP. J Clin Med, 14(3), 728. https://doi.org/10.3390/jcm14030728 DOI: https://doi.org/10.3390/jcm14030728
  4. Chandler TR, Furmanek S, Ramirez J. (2024). CURB-65 Scores Are Poor Predictors For Long-Term Mortality in Hospitalized Patients With CAP. Norton Healthcare Med J, 1(1). DOI: https://doi.org/10.59541/001c.115517
  5. García-García V, Gómez J, et al. (2024). Comparison of risk scores for predicting 30-day mortality in CAP patients. BMC Infect Dis, 24(97).
  6. Lim WS, van der Eerden MM, Laing R, et al. (2003). Defining CAP severity on presentation: derivation and validation study. Thorax, 58(5):377–382. DOI: https://doi.org/10.1136/thorax.58.5.377
  7. Metlay JP, Waterer GW, Long AC, et al. (2019). Diagnosis and treatment of adults with CAP. Am J Respir Crit Care Med, 200(7), e45–e67. DOI: https://doi.org/10.1164/rccm.201908-1581ST
  8. Ranzani OT, et al. (2017). SMART-COP, CURB-65 and PSI comparison. Clin Microbiol Infect, 23(12), 900–905.
  9. Zhang L, Wu T, Li Q. (2023). Atypical pathogens in community-acquired pneumonia. Infect Drug Resist, 16: 2927–2935.
  10. Wang Y, Liu F, et al. (2023). Radiographic features of community-acquired pneumonia and their diagnostic value. Front Med, 10:1120347.

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© 2025 The Author(s). Published by Journal of Health and Aging.