ASSESSMENT OF GLYCEMIC CONTROL IN FRAIL OLDER ADULTS WITH TYPE 2 DIABETES MELLITUS

Nguyễn Thanh Vy 1, 2 , Nguyễn Đặng Ngọc Trinh 1 , Lê Hữu Phần 1, 2 , Nguyễn Thị Mây Hồng 1 , Phạm Hòa Bình 1, 2 ,
1 Thong Nhat Hospital image/svg+xml
2 University of Medicine and Pharmacy at Ho Chi Minh City image/svg+xml
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DOI
10.63947/bvtn.v2i9.7
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Published
2026-10-01
Issue Vol. 2 No. 9 (2026): A Major Step Forward in Specialized Care: A Milestone Marked by the First Liver Transplant at Thong Nhat Hospital
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Original Research

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Nguyễn TV, Nguyễn ĐNT, Lê HP, Nguyễn TMH, Phạm HB. ASSESSMENT OF GLYCEMIC CONTROL IN FRAIL OLDER ADULTS WITH TYPE 2 DIABETES MELLITUS. JHA [Internet]. Vietnam; 2026 Oct. 1 [cited 2026 Oct. 16];2(9):55–60. https://tcsuckhoelaohoa.vn/bvtn/article/view/226 doi: 10.63947/bvtn.v2i9.7
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Abstract

Diabetes mellitus is increasingly prevalent among older adults, and glycemic control remains challenging. According to the 2025 American Diabetes Association (ADA) recommendations, HbA1c targets should be individualized based on frailty, functional and cognitive status, life expectancy, comorbidities, and vascular complications. This study aimed to determine the proportion of older patients achieving glycemic control targets and to examine the associations between geriatric factors and treatment effectiveness in patients with type 2 diabetes mellitus. A descriptive cross-sectional study was conducted from April to August 2025 at the Endocrinology Outpatient Clinic, Thong Nhat Hospital, Ho Chi Minh City. Among 185 patients, the median age was 68 years (64–75.5), and 45.4% achieved their HbA1c target. Multivariable logistic regression showed that frailty and high cardiovascular risk were independently associated with the likelihood of achieving the HbA1c target, with OR = 0.48 (95% CI: 0.25–0.92; p = 0.027) and OR = 0.57 (95% CI: 0.32–0.99; p = 0.047), respectively. Multimorbidity and polypharmacy were not significantly associated with achieving the HbA1c target. The proportion of patients achieving their HbA1c target remained limited. Frailty and high cardiovascular risk were independently associated with the likelihood of achieving treatment targets.

Keywords

older adults frailty glycemic control

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