Research

145 Items

CURRENT SITUATION AND BARRIERS TO HPV VACCINATION AMONG FEMALE NURSING STUDENTS AT TRA VINH UNIVERSITY, VIETNAM, 2024

Lam Tai Hoang Hieu, Ngo Le Hoang Giang, Thach Lan Trinh

Page 112-116

Downloads: 327 Views: 672

DOI: 10.63947/bvtn.v1i5.17

Cervical cancer is one of the most common cancers in women and can be prevented through HPV vaccination. However, HPV vaccination coverage in Vietnam remains low, especially among healthcare students. This study aimed to assess the status and barriers to HPV vaccination among female nursing students at Tra Vinh University. A descriptive cross-sectional study was conducted among 233 female nursing students from May to July 2024. Data were collected using a self-administered questionnaire and analyzed with SPSS 22.0, employing descriptive statistics, Chi-square tests, and logistic regression. Only 15.5% of students had received at least one dose of HPV vaccine, with 9.4% completing the full three-dose schedule. The main barriers included high cost (73.4%), concerns about side effects (28.8%), perception of unnecessary vaccination without prior sexual activity (22.3%), and lack of accurate information (21.5%). Most students had good knowledge and positive attitudes: 91.4% knew HPV vaccine prevents cervical cancer, 91.8% trusted its effectiveness, and 92.3% were willing to recommend it to peers. HPV vaccination coverage among female nursing students remains low, largely due to financial constraints and insufficient information. Strengthened health education and financial support policies are essential to improve vaccination uptake in this population.

Abstract:

Cervical cancer is one of the most common cancers in women and can be prevented through HPV vaccination. However, HPV vaccination coverage in Vietnam remains low, especially among healthcare students. This study aimed to assess the status and barriers to HPV vaccination among female nursing students at Tra Vinh University. A descriptive cross-sectional study was conducted among 233 female nursing students from May to July 2024. Data were collected using a self-administered questionnaire and analyzed with SPSS 22.0, employing descriptive statistics, Chi-square tests, and logistic regression. Only 15.5% of students had received at least one dose of HPV vaccine, with 9.4% completing the full three-dose schedule. The main barriers included high cost (73.4%), concerns about side effects (28.8%), perception of unnecessary vaccination without prior sexual activity (22.3%), and lack of accurate information (21.5%). Most students had good knowledge and positive attitudes: 91.4% knew HPV vaccine prevents cervical cancer, 91.8% trusted its effectiveness, and 92.3% were willing to recommend it to peers. HPV vaccination coverage among female nursing students remains low, largely due to financial constraints and insufficient information. Strengthened health education and financial support policies are essential to improve vaccination uptake in this population.

Surgical treatment has been the standard of care in selected cases with solid tumors or uterine benign diseases. However, a majority of patients are unable to undergo surgical resection because of the tumor locations, advanced stages, or poor general condition. For patients who are not suitable for surgery or unwilling to undergo surgical treatment, high-intensity focused ultrasound (HIFU) ablation surgery is a new option. HIFU is a novel non-invasive technique that can generate coagulative necrosis at a precise focal point within the body, without damaging to the surrounding structures of the target lesions, even within the path of the beam. Ultrasound guided HIFU (USgHIFU) was first used in the treatment of bone tumors in the 1990s. Over the last two decades, this technology has made significant progress and is now widely used in the treatment of various solid tumors and benign diseases of certain organs. Currently, both magnetic resonance imaging guidance focused ultrasound surgery (MRgFUS) and USgHIFU are commercially available. Each of these two types of HIFU systems has its own advantages in guidance. USgHIFU has higher treatment efficiency, with shorter treatment time, and can treat a wider range of diseases than that of MRgFUS. Recently, HIFU has been proven to be beneficial as an adjunct in the treatment of cardiovascular diseases. In addition, MRgFUS allows for non-invasive treatment of intracranial lesions is another significant advancement in the field of therapeutic ultrasound. Histotripsy was recently approved by the U.S. Food and Drug Administration (FDA) for hepatic targets. Last year, the Focused Ultrasound Foundation announced that focused ultrasound has been used for the treatment of over 170 diseases. As advances in engineering technology, including guidance techniques for the fusion of ultrasound and MRI, as well as optimization of transducer, are making HIFU treatments easier, safer, and more efficacious. This technique may play a key role in future clinical practice.

 

CONCORDANCE BETWEEN DIRECT MEASUREMENT OF LDL-C AND ESTIMATION BY THE EXTENDED MARTIN-HOPKINS EQUATION AT HIGH TRIGLYCERIDE

Mai Phùng Huyền My, Thái Hữu Khoa, Cao Thị Vân

Page 101-107

Downloads: 140 Views: 115

DOI: 10.63947/bvtn.v2i6.15

Cardiovascular disease remains one of the leading causes of mortality worldwide, and LDL-C is a critical risk factor. Although direct measurement of LDL-C using homogeneous enzymatic assays provides high accuracy, it remains costly and time-consuming. The Friedewald equation, while widely applied, reduces accuracy in patients with elevated triglyceride, whereas the extended Martin-Hopkins (eMH) equation has been proposed to overcome this limitation. This cross-sectional study was conducted on 626 patients at Thong Nhat Hospital with TG levels ranging from 400-800 mg/dL. LDL-C concentrations were determined using a homogeneous enzymatic method and estimated using both the Friedewald and eMH equations. Accuracy was assessed by Pearson’s/Spearman’s correlation coefficient, mean absolute error (MAE), root mean square error (RMSE), and concordance rate for risk reclassification. The eMH equation demonstrated a higher correlation with direct measurement compared to Friedewald (0,74 > 0,70), lower MAE and RMSE values (20,6 mg/dL and 27,8 mg/dL vs 42,3 mg/dL and 52,2 mg/ dL), and a higher concordance rate (39% vs 29%). In conclusion, the eMH equation showed superior accuracy and concordance within the TG range of 400-800 mg/dL compared with the Friedewald equation. Nevertheless, further multicenter studies and comparisons with reference β-quantification methods are warranted before broad public implementation.

As Vietnam’s population ages rapidly, the health system faces increasing demands for long-term, integrated, and person-centered care for older adults. To meet these challenges, the “Treatment Triangle” model has been proposed, comprising three interconnected pillars: (1) home and community-based care, (2) hospitalbased specialized treatment, and (3) rehabilitative and nursing care at dedicated centers. Together, these pillars form a continuum of care that emphasizes prevention, early detection, comprehensive management of chronic diseases, and recovery of physical and psychological function. This paper describes the structure, roles, and interconnections of each component and discusses how this model could serve as a sustainable and humane framework for geriatric care in Vietnam.

 

Evaluate the clinical efficacy of silver-containing antimicrobial dressings on superficial burn wounds. A prospective study involving 32 patients treated for thermal burns at the Trauma and Orthopedic Surgery Department of Thong Nhat Hospital. The patients were dressed with silver-containing antimicrobial bandages, and clinical efficacy was assessed based on the local wound progression. The dressing adhered well to the wound, was easy to change, and caused minimal pain and bleeding during dressing changes. The average treatment duration was 11.2 ± 5.8 days. Only 9.4% of patients experienced wound infection. Silver-containing antimicrobial dressings are effective in the clinical management of superficial thermal burn wounds.

Chronic subdural hematoma (CSDH) is a common condition in the elderly, often associated with a prior history of trauma and progressively worsening symptoms if not diagnosed and treated promptly. This study aims to describe the clinical characteristics, imaging findings, and surgical outcomes of patients with CSDH treated at Long Khanh Regional General Hospital from 2021 to 2024; A total of 34 patients diagnosed with CSDH underwent single-burr-hole surgical drainage between January 2021 and September 2024. The mean patient age was 68.4 ± 16.9 years, with males accounting for 88.2%. Trauma was the primary cause (52.9%), including falls in 29.4% of cases. Motor weakness was the most common symptom (64.7%), followed by headache (55.8%), altered consciousness (23.5%), and aphasia (20.6%). Most patients presented with mild traumatic brain injury (GCS 13–15, 76.5%), while coma was recorded in 8.8%. CT imaging showed a mean hematoma thickness of 21.1 ± 6.3 mm and a mean midline shift of 9.4 ± 4.8 mm; unilateral CSDH was observed in 70.6% of cases. All patients underwent single-burr-hole surgery. Postoperatively, 88.2% achieved a GCS of 15. There were no cases of infection or intraoperative bleeding. Recurrence occurred in four patients, including one requiring reoperation after three weeks; the mortality rate was 2.9%. The average hospital stay was 10.7 ± 5.4 days. At discharge, 73.5% of patients had good outcomes, and 73.5% returned to normal life within one month. In conclusion, single-burr-hole drainage for chronic subdural hematoma is effective, safe, and associated with favorable outcomes, low complication rates, and good functional recovery in most patients.

Colorectal cancer is one of the most common malignancies with high incidence and mortality rates. KRAS and BRAF mutations play a crucial role in its pathogenesis and prognosis, but their association with clinical characteristics in Vietnam requires further investigation. To investigate the prevalence of KRAS and BRAF mutations in colorectal cancer patients and analyze their relationship with clinical, epidemiological, and disease-stage features. A retrospective descriptive study was conducted on 92 colorectal cancer patients diagnosed and treated at Thong Nhat Hospital from February 2020 to December 2024. Data included demographic characteristics, clinical symptoms, tumor location, disease stage, and genetic mutation test results. The median age of patients was 66, with a male/female ratio of 2.1. Common symptoms included abdominal pain (71.7%) and bloody stools (38%). The mutation rates were 35.9% for KRAS (predominantly G12D and G12V), 6.5% for BRAF, and no NRAS mutations were detected. KRAS and BRAF mutations showed no significant association with age, gender, clinical symptoms, or disease stage (p>0.05), but were linked to peripheral lymphadenopathy (p=0.035). KRAS and BRAF mutations are relatively common in colorectal cancer patients but are not strongly associated with clinical features or disease stage. Genetic testing remains essential for personalized diagnosis and treatment.

Appendiceal peritonitis is a common surgical emergency, particularly dangerous in the elderly due to atypical symptoms and high risk of complications. However, studies on the clinical and paraclinical characteristics of this condition in this age group in Vietnam remain limited. To describe the clinical and paraclinical features of appendiceal peritonitis in elderly patients at Thong Nhat Hospital, while analyzing risk factors associated with complications and hospital stay duration. A retrospective cross-sectional descriptive study was conducted on 39 patients aged ≥60 diagnosed with appendiceal peritonitis and undergoing surgery at Thong Nhat Hospital from October 2023 to October 2024. The mean age of patients was 71.9, with a nearly equal male/female ratio (48.7%/51.3%). Right lower quadrant pain was the most common symptom (48.7%), but only 20.5% of patients had mild fever. Leukocytosis (≥10 G/L) was observed in 74.4% of cases, and CRP ≥10 mg/L in 41%. CT scans detected infiltration in 76.9% of patients. Comorbidities such as hypertension (38.5%) and diabetes (20.5%) increased the risk of complications and prolonged hospital stays. The age group ≥70 had a higher rate of appendiceal necrosis (66.7%) compared to the 60–69 age group (38.1%). Appendiceal peritonitis in the elderly presents with atypical clinical features, often leading to delayed diagnosis. Comorbidities and advanced age are significant risk factors for severe complications. Imaging plays a crucial role in early detection and disease severity assessment.

CLINICAL AND PARACLINICAL CHARACTERISTICS AND TREATMENT OUTCOMES OF ELDERLY PATIENTS WITH ISCHEMIC STROKE AT THONG NHAT HOSPITAL

Nguyễn Thị Phương Nga, Nguyễn Phạm Hoàng Long, Trần Thị Hồng Nhung

Page 59-64

Downloads: 84 Views: 193

DOI: 10.63947/bvtn.v2i8.8

This study aimed to characterize the clinical, paraclinical, and therapeutic features of ischemic stroke in patients aged 60 years and older treated at Thong Nhat Hospital. A prospective descriptive design was applied to 242 patients aged ≥60 years who were admitted with acute ischemic stroke to the Department of Neurology, Thong Nhat Hospital, between February and August 2025. The median age of the cohort was 71 years (69 years in males and 76 years in females). Males accounted for 63,4% of the sample. Hypertension was the most prevalent risk factor, present in 75,6% of patients, followed by diabetes mellitus and dyslipidemia, while atrial fibrillation was rare. The mean LDL-cholesterol level was 117,9 ± 50,7 mg/dl. At admission, low NIHSS scores (0–5) were observed in 58,8% of males and 57,3% of females. Favorable recovery (low NIHSS scores) after treatment was achieved in 80,4% of males and 64% of females. Female sex is associated with poorer treatment outcomes. The rate of reperfusion therapy was 21,1%. Among identifiable etiologies, small vessel disease was the most common, accounting for 26,4%. However, 47,9% of patients had undetermined causes. Ischemic stroke patients aged ≥60 years at Thong Nhat Hospital exhibit characteristics consistent with global trends, while also presenting distinctive features regarding risk factors and etiologies.

CLINICAL AND LABORATORY CHARACTERISTICS AND EVALUATION OF CURB-65 IN RISK STRATIFICATION OF COMMUNITY ACQUIRED PNEUMONIA AT THONG NHAT HOSPITAL

Hoàng Thái Dương, Hoàng Văn Quang, Ngô Thế Hoàng, Nguyễn Duy Cường, Nguyễn Thị Phương Thanh

Page 95-100

Downloads: 288 Views: 426

DOI: 10.63947/bvtn.v1i4.16

This study aimed to: (1) describe the clinical and paraclinical characteristics of patients with CAP; and (2) assess the prognostic value of the CURB-65 score in determining disease severity and predicting the need for hospitalization. A retrospective descriptive study was conducted on 250 adult patients diagnosed with CAP at Thong Nhat Hospital (Vietnam) between April 2023 and April 2025. Clinical symptoms, laboratory findings, chest radiography, and CURB-65 scores were collected and analyzed using SPSS 20.0. The correlation between CURB-65 and hospitalization was assessed using chi-square tests. The most common clinical symptoms were productive cough (74%), fever (67.6%), and dyspnea (54%). Radiographic abnormalities predominantly involved the right lung (43.6%). Elevated CRP (>5 mg/dL) and leukocytosis (>10,000 cells/mm³) were observed in 89.2% and 61.6% of patients, respectively. Among hospitalized patients, the majority had CURB- 65 scores ≥2 (p < 0.001). All patients with scores ≥4 were admitted to the ICU. CURB-65 is a simple and effective tool for initial risk stratification in patients with CAP. Its predictive value for hospitalization and intensive care admission supports its routine use in clinical practice, particularly in resource-limited settings.

CHARACTERISTICS OF CAUSES, CLINICAL, AND SUBCLINICAL SYMPTOMS IN ADULT PATIENTS WITH IRON DEFICIENCY ANEMIA AT DONG THAP GENERAL HOSPITAL

Trần Thanh Tòng, Phạm Quốc Duy, Dương Phước Bình, Võ Tấn Phát

Page 108-113

Downloads: 166 Views: 238

DOI: 10.63947/bvtn.v2i6.16

Iron deficiency anemia (IDA) constitutes a significant global health issue. Recent studies indicate that 8-15% of iron deficiency anemia cases are attributable to gastrointestinal malignancies.  This study presents a series of cases to elucidate the clinical and paraclinical characteristics, etiologies of iron deficiency anemia (IDA), and to assess the correlation among certain variables in patients.  The study results included 119 patients aged 16 years and older diagnosed with iron deficiency anemia (IDA) from June 2024 to May 2025 indicated a median age of 60 ± 17.4 years, with 59.7% being female.  Prevalent symptoms of anemia include dizziness, vertigo (96.6%), and pallor of the skin and mucous membranes (82.4%).  The majority of individuals with severe anemia (87.4%) exhibited inadequate bone marrow response (RPI = 0.3 ± 0.1).  The median ferritin level was 10.3 ± 7.5 ng/mL, exhibiting a strong correlation with red blood cell shape (MCV, MCH, MCHC) and transferrin levels.  The primary cause was chronic iron deficiency, with 9.2% attributed to gastrointestinal neoplasms, predominantly affecting men at a rate of 72.7%.  Studies indicate that TMTS is a prevalent condition, particularly among women and the elderly.  It is crucial to screen for the etiology of iron deficiency, particularly gastrointestinal neoplasms, in elderly males.

CHARACTERISTICS OF BRAIN-DEAD ORGAN DONORS AT THONG NHAT HOPITAL

Trương Vân Anh, Đào Ngô Quyền, Nguyễn Anh Tùng, Nguyễn Thị Thanh Thuỷ

Page 122-128

Downloads: 224 Views: 248

DOI: 10.63947/bvtn.v1i4.20

The global demand for organ transplantation is steadily increasing; however, the availability of donor organs remains limited. Optimal management of potential organ donors from the time of brain death diagnosis until the completion of organ procurement is crucial to maximize graft function. This research presents a case series describing three successful cases of brain-dead organ donation conducted at Thong Nhat Hospital. The donated organs included liver, kidneys, heart, and corneas, which were subsequently transplanted at various medical centers. To ensure graft survival, all donated organs must be maintained in a physiologically stable condition until procurement. Providing intensive care and protecting the organs of the donor is the first step toward ensuring a successful transplant in the future.

CHARACTERISTICS OF ARTERY BLOOD GAS IN EXACERBATIONS  OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE PATIENTS

Phùng Thảo My, Ngô Thế Hoàng, Lê Thị Điệp, Phạm Thị Thu Hồng

Page 94-99

Downloads: 325 Views: 546

DOI: 10.63947/bvtn.v1i2.13

To evaluate arterial blood gas test results in patients with acute exacerbation chronic obstructive pulmonary disease (AECOPD). Cross-sectional descriptive study, evaluating blood gas results on 150 patients diagnosed with AECOPD, inpatient treatment at the Respiratory Department in Thong Nhat Hospital from January 2023 - March 2024.  The majority of patients (80%) have decreased PaO2 and 60% of patients have increased PaCO2. The average value of some blood gas indicators: pH 7.37 ± 0.08, PaO2 61.2 ± 10.5, PaCO2 48.3 ± 8.2, HCO3- 27.1 ± 3.4. There were 126 patients with COPD exacerbated hospitalization (84%) with respiratory failure manifested in arterial blood gas Respiratory failure characteristics according to arterial blood test in the study were mainly increased PaCO2 accounting for 30%, in patients with mixed respiratory failure had 26% and reduced respiratory depression PaO2 had 32%.  Arterial blood gas is a significant test for diagnosis the respiratory failure and discovered acid- base disorders.

CASE REPORT: MULTI-MATERIAL ABDOMINAL WALL RECONSTRUCTION SURGERY AFTER MASSIVE DESMOID TUMOR RESECTION

Phạm Quang Nhật, Nguyễn Thanh Phong

Page 132-135

Downloads: 181 Views: 407

DOI: 10.63947/bvtn.v1i3.20

Abdominal wall aggressive fibromatosis (Desmoid tumor) is a rare, locally invasive tumor with a high recurrence rate. This study reports a case of surgical resection of a large tumor and multi-material abdominal wall reconstruction, evaluating functional and aesthetic outcomes. A 29-year-old male presented with a 10x15cm abdominal wall mass, diagnosed as Desmoid tumor via biopsy. The patient underwent complete tumor resection, resulting in a significant abdominal defect. Reconstruction was performed using a combination of intraperitoneal onlay mesh (IPOM), rectus abdominis muscle flap, and fascia flap. Pathology confirmed R0 resection. The patient was discharged on day 7 without major complications. At 1-year follow-up, results showed excellent aesthetic and functional recovery with no recurrence. Surgical resection of Desmoid tumors combined with multi-material abdominal wall reconstruction is a feasible approach, ensuring long-term functional and aesthetic success. This case highlights the importance of selecting appropriate reconstruction techniques for large post-resection defects.

CASE REPORT OF RECURRENT RETROPERITONEAL LIPOSARCOMA

Vũ Lộc, Hồ Hữu Đức, Hoàng Anh Bắc

Page 128-131

Downloads: 291 Views: 479

DOI: 10.63947/bvtn.v1i3.19

Retroperitoneal liposarcoma is a rare condition, accounting for approximately 15% of adult soft tissue tumors and has a high recurrence rate. We report a case of recurrent retroperitoneal tumor to evaluate and review treatment approaches. We report a case of a 45-year-old female with a history of surgical resection of a large pelvic retroperitoneal liposarcoma (23x12cm) in 2020, which was well-differentiated (Grade I) but had tumor cells in an ovarian cyst (Stage IIIB). After 3 years of follow-up, the patient was found to have a tumor recurrence at the lower pole of the right kidney measuring 37x38mm on CT scan. The patient underwent complete surgical resection of the recurrent tumor with negative margins (R0), and pathology confirmed well-differentiated liposarcoma (Grade I). After 9 months of followup, no recurrence has been detected. This case emphasizes the importance of regular postoperative follow-up, which helps detect early recurrence when tumors are still small, increases the possibility of complete treatment, and improves patient prognosis.

BOTULINUM TOXIN IN AESTHETIC CONTOURING: FROM FACIAL SLIMMING TO BODY CONTOURING

Nguyễn Thị Trà My, Nguyễn Ảnh Sang

Page 78-84

Downloads: 61 Views: 110

DOI: 10.63947/bvtn.v2i8.11

Botulinum toxin type A (BTX-A) is one of the key tools in non-invasive aesthetic contouring. Initially used primarily for the reduction of dynamic wrinkles, BTX-A is now widely applied in facial slimming and body contouring. However, differences in anatomical characteristics, muscle physiology, and treatment responses across anatomical regions have not yet been systematically synthesized. Materials and methods: This study was conducted as a narrative review, based on a structured search of the PubMed, Scopus, and Web of Science databases for studies related to the application of BTX-A in facial and body aesthetic contouring. Results: BTX-A demonstrates significant effectiveness in reducing muscle volume and improving contour across various anatomical regions. Factors influencing outcomes include dosage, injection technique, muscle characteristics, and individual patient factors. Notably, substantial differences between facial and body contouring highlight the need for region-specific treatment approaches. Conclusion: BTX-A is an effective and safe modality in aesthetic contouring. Optimization of treatment outcomes requires a thorough understanding of anatomy, the mechanism of action, and individualized injection strategies. Future research should focus on dose standardization and the development of personalized treatment models to enhance both efficacy and safety.

 

BISPHOSPHONATE INDUCED OSTEONECROSIS OFTHE JAWS

Nguyen Viet Phuong, Nghiem Thi Hong Nhung

Page 86-94

Downloads: 146 Views: 266

DOI: 10.63947/bvtn.v2i7.11

Bisphosphonate (BP) is a group of drugs used to treat osteoporosis, multiple myeloma, skeletal metastasis cancer. BP’s mechanism of action is to reduce bone resorption by inhibiting the osteoclasts activity. Therefore, the indication of BP is increasingly widespread and becomes the first class of drugs in the treatment of osteoporosis. At Frienship Hospital, over the past five years, we have encountered 12 cases of bisphosphonate-related osteonecrosis of the jaw (BRONJ) at various stages. The key message we wish to convey in this report is to kindly encourage close collaboration between internal medicine specialists and oral maxillofacial surgeons during bisphosphonate therapy, in order to minimize the risk of BRONJ complications for patients.

Abstract:

Bisphosphonate (BP) is a group of drugs used to treat osteoporosis, multiple myeloma, skeletal metastasis cancer. BP’s mechanism of action is to reduce bone resorption by inhibiting the osteoclasts activity. Therefore, the indication of BP is increasingly widespread and becomes the first class of drugs in the treatment of osteoporosis. At Frienship Hospital, over the past five years, we have encountered 12 cases of bisphosphonate-related osteonecrosis of the jaw (BRONJ) at various stages. The key message we wish to convey in this report is to kindly encourage close collaboration between internal medicine specialists and oral maxillofacial surgeons during bisphosphonate therapy, in order to minimize the risk of BRONJ complications for patients.

BALANCE IMPROVEMENT IN OLDER ADULTS WITH TAEKWONDO

Trần Bình Minh

Page 16-20

Downloads: 117 Views: 143

DOI: 10.63947/bvtn.v2i6.3

Impaired balance in older adults can directly lead to falls, leading to injuries, reduced quality of life, and increased dependence in daily activities. To diversify neuromotor exercises, evidence on the effectiveness of Taekwondo has been reviewed. Searches using relevant keywords reported that Taekwondo significantly improves both static and dynamic balance measures in individuals over 65 years old. Additionally, the findings suggest that Taekwondo may enhance exercise adherence among participants. These results support the potential of Taekwondo as a exercise to improve balance for older adults, although further high-quality evidence is needed.

AURICULAR ELECTROACUPUNCTURE FOR FUNCTIONAL GASTROINTESTINAL DISORDERS: A PRELIMINARY STUDY AT THE DEPARTMENT OF TRADITIONAL MEDICINE, THONG NHAT HOSPITAL

Nguyen Thi Que Chi, Hoang Thi Hong Nhung, Nguyen Quoc Phong, Le Thi Hanh, Nguyen Thi Truc Nha, Vu Thị Ly Na

Page 68-73

Downloads: 425 Views: 393

DOI: 10.63947/bvtn.v1i5.10

This study was conducted to evaluate the therapeutic efficacy and safety of electro-auricular acupuncture in the treatment of functional gastrointestinal disorders, as classified by Traditional Medicine. Thirty patients with digestive disorders were enrolled and received daily electro-auricular acupuncture for 14 consecutive days. Symptom severity was assessed at baseline D0, D7, and D14 using a standardized questionnaire. In the excess pattern group, a statistically significant improvement was observed in certain symptoms by day 7 (abdominal pain, p=0,04; borborygmus/bloating, p=0,008), with most symptoms showing marked reduction by day 14 (p<0,05). For the deficiency pattern group, most symptoms demonstrated significant improvement primarily at D14 (p<0,05); however, specific symptoms such as “sallow complexion/cold limbs” and “fatigue/poor appetite” showed improvement only at this later time point. The treatment was well-tolerated, and no serious adverse events were reported. Minor, self-limited side effects included pain at insertion (10%), mild bleeding (6,7%), and needle faint (3,3%). The findings suggest that electro-auricular acupuncture is an effective intervention for improving the symptoms of digestive disorders in both excess and deficiency patterns and possesses a favorable safety profile.

 

ASSESSMENT OF QUALITY OF LIFE AND RELATED FACTORS IN ELDERLY PEOPLE WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE AT THE RESPIRATORY CLINIC, THONG NHAT HOSPITAL

Lê Thị Điệp, Hoàng Văn Quang, Ngô Thế Hoàng, Nguyễn Duy Cường, Huỳnh Thị Thanh Ngân

Page 101-106

Downloads: 393 Views: 570

DOI: 10.63947/bvtn.v1i4.17

To evaluate the quality of life and associated factors among elderly patients with COPD attending the Respiratory Outpatient Clinic, Thong Nhat Hospital. A cross-sectional study was conducted on 240 patients aged ≥60 years with confirmed COPD according to GOLD 2025 criteria. Clinical data were collected, and QoL was assessed using the validated Vietnamese version of the St. George’s Respiratory Questionnaire for COPD patients (SGRQ-C). Statistical analysis included descriptive statistics, bivariate tests, and multivariate logistic regression to identify independent factors associated with poor QoL. The mean age was 72 ± 8 years; 41.3% were 60–69 years, 41.3% were 70–79 years, and 40.8% were ≥80 years. Males accounted for 86.2%; 75.4% had a history of smoking, and 71.7% had at least one comorbidity. The mean total SGRQ-C score was 50.2 ± 19.6, with the symptoms domain being the most impaired (58.5 ± 19.5). Overall, 47.9% of patients had low or very low QoL. Multivariate analysis showed that age ≥70 (OR=1.7), female gender (OR=3.1), history of hospitalization, need for caregiver support (OR=1.2), GOLD group E (OR=1.2), and acute exacerbations requiring hospitalization (OR=1.3) were independently associated with poor QoL (p<0.05). Elderly patients with COPD at Thong Nhat Hospital had significantly impaired QoL, particularly in physical activity. Advanced age, female gender, severe airflow limitation, frequent exacerbations, comorbidities, and smoking were key determinants of poor QoL. Routine QoL assessment and comprehensive interventions—including smoking cessation, pulmonary rehabilitation, comorbidity management, and psychosocial support—are essential to improve outcomes in this vulnerable population.

ASSESSMENT OF NUTRITIONAL STATUS AND RELATED FACTORS IN PATIENTS AFTER LAPAROSCOPIC GASTRECTOMY AT THONG NHAT HOSPITAL

Nguyễn Văn Hưng, Đỗ Duy Đạt, Phạm Thị Hiền Diệu, Nguyễn Thanh Thuỷ, Trần Tố Trinh

Page 100-106

Downloads: 61 Views: 100

DOI: 10.63947/bvtn.v2i8.14

To describe nutritional status and selected related factors in patients after laparoscopic gastrectomy at Thong Nhat Hospital. This retrospective descriptive study included 30 patients who underwent laparoscopic gastrectomy from January 2021 to December 2024 and had available baseline and 3-month postoperative follow-up data. Variables included clinical characteristics, type of surgery, adjuvant chemotherapy, gastrointestinal symptoms, dietary tolerance, oral nutritional supplement (ONS) use, micronutrient supplementation, anthropometric indices, and biochemical parameters. Nutritional status was classified using the Subjective Global Assessment (SGA). Dietary intake was assessed from follow-up records/nutrition notes, focusing on meal frequency, tolerance, ONS use, and clinically recorded achievement of energy–protein intake. Given the retrospective design and small sample size, comparisons were considered exploratory and intended to describe between-group differences rather than infer causality. Most patients were male, with a mean age of nearly 60 years; gastric cancer was the main diagnosis. At 3 months postoperatively, patients had an average weight loss of approximately 9–10%, decreased BMI, and lower albumin and hemoglobin levels. Approximately 40% of patients were classified as malnourished or at risk by SGA. Common gastrointestinal symptoms included anorexia, nausea/vomiting, and dumping syndrome/symptoms suggestive of dumping. Malnutrition after laparoscopic gastrectomy requires proactive monitoring. Periodic screening, assessment of dietary tolerance, standardized nutritional counseling, appropriate micronutrient supplementation, and larger prospective studies are needed to further evaluate associated factors.

ASSESSMENT OF HLA-B27 EXPRESSION BY FLOW CYTOMETRY AND ITS CLINICAL RELEVANCE IN ANKYLOSING SPONDYLITIS

Nguyễn Quang Đẳng, Huỳnh Thị Thanh Thuý, Nguyễn Thị Mỹ Linh

Page 95-100

Downloads: 145 Views: 130

DOI: 10.63947/bvtn.v2i6.14

Ankylosing spondylitis (AS) is a chronic inflammatory disease strongly associated with the genetic marker HLA-B27. HLA-B27 testing plays an important role in supporting early diagnosis. Flow cytometry is a novel method with high potential for detection of HLA-B27. To determine the prevalence of HLA-B27 positivity and negativity among AS patients and to evaluate its association with biological characteristics within the study population. A retrospective descriptive study was conducted at Thong Nhat Hospital from January to July 2025 on patients diagnosed with AS based on ICD code M45. HLA-B27 testing was performed using the flow cytometry technique. Data were analyzed using descriptive statistics and correlation analysis via Microsoft Excel 2021. Among 248 patients diagnosed with AS (ICD M45), females were predominant (male:female ratio = 1:1.5). The average age of the cohort was 44.6 ± 14.9 years. The rate of HLA-B27 positivity was 12% (30/248), significantly lower than in previous studies. Patients with HLA-B27 positivity had a younger mean age at disease onset compared to the negative group (40.9 ± 15.4 vs. 45.1 ± 14.8 years; p = 0.048). No statistically significant difference in gender distribution was observed between the two groups (p > 0.05), although a higher proportion of females was noted in the HLA-B27 negative group. In Conclusions, The low HLA-B27 positivity rate in this study may reflect population characteristics and broader screening criteria. HLA-B27 positivity was associated with younger age at disease onset, suggesting its role not only in diagnosis but also in clinical presentation. Flow cytometry proved effective in detecting HLA-B27 and shows potential for broader clinical application.

ASSESSMENT OF HEART FAILURE KNOWLEDGE IN OUTPATIENTS WITH CHRONIC HEART FAILURE AT THONG NHAT HOSPITAL

Hoang Thi Tuyet, Le Quoc Hung, Nguyen Thi Thu Huong, Ngo Thi Hao, Nguyen Thi Huong, Nguyen Van Be Hai

Page 30-38

Downloads: 139 Views: 286

DOI: 10.63947/bvtn.v2i7.4

Chronic heart failure is one of the leading causes of hospitalizations, impaired quality of life, and increased socioeconomic burden. Adequate disease awareness and effective self-care are key factors in improving prognosis and reducing hospital readmissions. A crosssectional descriptive study was conducted from January 1 to May 31, 2025, involving 200 patients. The tools used included the Dutch Heart Failure Knowledge Scale (DHFKS), a qualityof-life questionnaire, and a self-care assessment. Results: 66% of patients were aged ≥60 years, 94.5% had health insurance, and 78.5% resided in urban areas. Heart failure with reduced ejection fraction (HFrEF) accounted for 73.5%, significantly higher among patients aged ≥60 years (78.8%, p = 0.026). Hypertension (91%) and dyslipidemia (77%) were the most common comorbidities. A total of 78% of patients demonstrated good knowledge of heart failure. Regarding self-care behaviors, most adhered to a low-salt diet and regular weight monitoring, though physical activity remained suboptimal. Dyspnea and lower limb edema significantly impacted quality of life. When symptoms occurred, patients commonly contacted healthcare providers. Conclusions: The majority of outpatients with chronic heart failure demonstrated good disease awareness; however, improvements in self-care practices and multidimensional support are needed to enhance quality of life and reduce disease burden.

Abstract:

Chronic heart failure is one of the leading causes of hospitalizations, impaired quality of life, and increased socioeconomic burden. Adequate disease awareness and effective self-care are key factors in improving prognosis and reducing hospital readmissions. A crosssectional descriptive study was conducted from January 1 to May 31, 2025, involving 200 patients. The tools used included the Dutch Heart Failure Knowledge Scale (DHFKS), a qualityof-life questionnaire, and a self-care assessment. Results: 66% of patients were aged ≥60 years, 94.5% had health insurance, and 78.5% resided in urban areas. Heart failure with reduced ejection fraction (HFrEF) accounted for 73.5%, significantly higher among patients aged ≥60 years (78.8%, p = 0.026). Hypertension (91%) and dyslipidemia (77%) were the most common comorbidities. A total of 78% of patients demonstrated good knowledge of heart failure. Regarding self-care behaviors, most adhered to a low-salt diet and regular weight monitoring, though physical activity remained suboptimal. Dyspnea and lower limb edema significantly impacted quality of life. When symptoms occurred, patients commonly contacted healthcare providers. Conclusions: The majority of outpatients with chronic heart failure demonstrated good disease awareness; however, improvements in self-care practices and multidimensional support are needed to enhance quality of life and reduce disease burden.

Colonic diverticulitis is increasing in Asia, yet data on clinical patterns in Vietnam remain limited. This study aimed to evaluate the clinical, laboratory, imaging characteristics, and treatment outcomes at Thong Nhat Hospital. A retrospective descriptive study was conducted on 105 patients from January 1 to September 1, 2025. Data on demographics, clinical features, laboratory tests, CT findings, WSES classification, treatment strategies, and outcomes were collected and analyzed using SPSS 26.0, with p < 0.05 considered statistically significant. The mean age was 53.9 ± 20.0 years, with 31.4% aged ≥65. Males accounted for 67.6%. The most common symptom was right lower quadrant pain (55.2%). CT revealed diverticula mainly in the sigmoid colon (40.0%), cecum (37.1%), and right colon (19.0%). WSES stages were: 1a (57.1%), 1b (19.0%), 2a (11.4%), 2b (7.6%), 3 (3.8%), and 4 (1.0%). Medical treatment was applied in 89.5% of cases, percutaneous drainage in 1.0%, and surgery in 9.5%. The mean hospital stay was 7.6 ± 4.4 days, significantly longer in complicated cases and those requiring invasive interventions (p < 0.05). Colonic diverticulitis in Vietnam often affects middle-aged males, with location varying by age: cecum/right colon in younger patients and sigmoid colon in the elderly. CT-scan plays a crucial role in diagnosis, staging, and guiding treatment.

Abstract:

Colonic diverticulitis is increasing in Asia, yet data on clinical patterns in Vietnam remain limited. This study aimed to evaluate the clinical, laboratory, imaging characteristics, and treatment outcomes at Thong Nhat Hospital. A retrospective descriptive study was conducted on 105 patients from January 1 to September 1, 2025. Data on demographics, clinical features, laboratory tests, CT findings, WSES classification, treatment strategies, and outcomes were collected and analyzed using SPSS 26.0, with p < 0.05 considered statistically significant. The mean age was 53.9 ± 20.0 years, with 31.4% aged ≥65. Males accounted for 67.6%. The most common symptom was right lower quadrant pain (55.2%). CT revealed diverticula mainly in the sigmoid colon (40.0%), cecum (37.1%), and right colon (19.0%). WSES stages were: 1a (57.1%), 1b (19.0%), 2a (11.4%), 2b (7.6%), 3 (3.8%), and 4 (1.0%). Medical treatment was applied in 89.5% of cases, percutaneous drainage in 1.0%, and surgery in 9.5%. The mean hospital stay was 7.6 ± 4.4 days, significantly longer in complicated cases and those requiring invasive interventions (p < 0.05). Colonic diverticulitis in Vietnam often affects middle-aged males, with location varying by age: cecum/right colon in younger patients and sigmoid colon in the elderly. CT-scan plays a crucial role in diagnosis, staging, and guiding treatment.

ASSESSING THE IMPACT OF ORGANIZATIONAL CULTURE ON EMPLOYEE JOB SATISFACTION AND ENGAGEMENT AT THONG NHAT HOSPITAL

Cao Thị Hoài, Võ Thành Toàn, Cảnh Chí Hoàng, Đinh Kiệm, Nguyễn Thị Thanh Quang, Lê Thị Kim Cương, Nguyễn Văn Tài, Lê Đình Thanh

Page 38-44

Downloads: 342 Views: 518

DOI: 10.63947/bvtn.v1i4.6

Employee job satisfaction and organizational commitment are key factors that determine the effectiveness, stability, and professional development of hospitals in general and public hospitals in particular. This study aims to explore and measure the factors affecting job satisfaction and employee engagement in the healthcare sector from the perspective of organizational culture. Research data was collected from 499 healthcare workers currently employed at Thong Nhat Hospital. Among them, 324 were female (64.9%) and 175 were male (35.1%). The VIF analysis results show that the observed variables had a maximum value of 8.010 and a minimum of 0.713. The test for multicollinearity violations revealed 12 direct impact relationships indicating employee job satisfaction. Of the 11 established factors, only 5 relationships corresponding to 5 factors showed statistical significance at the 5% level: reward and recognition (β = 0.217, p < 0.0001), teamwork (β = 0.200, p < 0.0001), fair compensation (β = 0.157, p < 0.0001), integrity promotion (β = 0.165, p = 0.002), and training and advancement (β = 0.137, p = 0.004). Bootstrapping results showed that 3 moderating variables were not statistically significant, as their p-values were greater than 0.05. There are five factors that positively influence job satisfaction and employee commitment in healthcare, ranked from highest to lowest impact: reward and recognition, teamwork, fair compensation, integrity promotion, and training and advancement.