Research

Left ventricular noncompaction cardiomyopathy (LVNC) can lead to ventricular arrhythmias and may be misdiagnosed as arrhythmia-induced cardiomyopathy (AiCM). While LVNC is associated with genetic abnormalities, AiCM is triggered by arrhythmias and is typically reversible once the arrhythmia is eliminated. We report the case of a 59-year-old woman with LVNC carrying three TTN gene variants: c.100804A>T (p.Met33602Leu, exon 358), c.59200C>G (p.Pro19734Ala, exon 300), and c.52052T>C (p.Val17351Ala, exon 273). The patient was initially diagnosed with AiCM but showed no recovery of left ventricular function after successful catheter ablation of ventricular arrhythmias. Echocardiography and cardiac magnetic resonance imaging confirmed the LVNC phenotype. This case highlights the importance of distinguishing between these two entities in clinical practice.

 Laparoscopic restoration of intestinal continuity after Hartmann’s procedure offers significant benefits but remains a considerable challenge for gastrointestinal surgeons. To evaluate the feasibility, safety, and efficacy of laparoscopic colostomy closure after Hartmann’s procedure at Thong Nhat Hospital. A retrospective descriptive analysis was conducted on 35 cases from February 2017 to May 2025. Patients who had undergone Hartmann’s procedure with an end colostomy and received laparoscopic intestinal continuity restoration were included. The laparoscopic success rate was 85.71%. Major complications included surgical site infection (30%), anastomotic leakage, and intestinal obstruction (3% each). The average operative time was 162 minutes, and the mean hospital stay was 9.3 days. There were no mortality cases. Laparoscopic reversal of Hartmann’s procedure is a feasible, safe, and effective method with a high success rate and low complication rate.

To assess patients’ average level of knowledge regarding coronary artery disease and its associated factors at Tra Vinh Provincial General Hospital in the year 2024. A descriptive cross-sectional study was conducted on 128 patients diagnosed with coronary artery disease who came for examination and surgical treatment at the Cardiology Clinic at Tra Vinh Provincial General Hospital from May 2024 to July 2024 using the CADE-Q SV questionnaire. Our research results showed that 76.6% of patients had average knowledge and 23.7% of patients had poor knowledge; no patients had good knowledge; the rate of patients answering correctly for all questions was 45.04%; there was no correlation found between the knowledge of patients with coronary artery disease at Tra Vinh General Hospital and the factors surveyed at the time of the survey. Our research results showed that the knowledge of patients with coronary artery disease at Tra Vinh General Hospital in this study was still low, and there was no factors related to the rate of patients’ knowledge about coronary artery disease have been found.

The treatment of community-acquired pneumonia (CAP) has become increasingly challenging due to the growing antimicrobial resistance among bacterial pathogens. Rational antibiotic use is a key determinant of treatment effectiveness in patients with CAP. To investigate antimicrobial resistance patterns and antibiotic utilization in the treatment of communityacquired pneumonia at Hoc Mon Regional General Hospital. A descriptive cross-sectional study was conducted using 270 medical records of hospitalized patients diagnosed with communityacquired pneumonia at Hoc Mon Regional General Hospital from July 2024 to September 2024. The median age of patients was 69 years (interquartile range, 59–77), with 65.2% aged over 65 years. Gram-negative bacteria accounted for 93.2% of isolated pathogens, predominantly Klebsiella pneumoniae (24.1%) and Pseudomonas aeruginosa (15.5%). Klebsiella pneumoniae demonstrated susceptibility rates ranging from 70% to 100% to beta-lactam/beta-lactamase inhibitor combinations. Pseudomonas aeruginosa showed high susceptibility rates (89–100%). The most commonly prescribed empirical antibiotics were ceftriaxone (51.9%) and levofloxacin (40.4%). Overall appropriateness of empirical antibiotic therapy was 41.5%. Older patients, higher Charlson score, higher CURB-65 score, and ICU admission were factors associated with treatment failure. The antibiotics recommended for the treatment of community-acquired pneumonia remain largely effective against common causative pathogens at the hospital. However, adherence to treatment guidelines for empirical antibiotic selection was suboptimal, underscoring the need for targeted interventions to promote rational antibiotic use and improve the quality of infection management.

Chronic Obstructive Pulmonary Disease (COPD) is one of the leading causes of mortality and disability worldwide. Among elderly patients, COPD not only reduces quality of life but also places a significant burden on healthcare systems. Chronic inflammation plays a key role in the pathogenesis of COPD. In recent years, peripheral blood inflammatory markers such as the neutrophil-to-lymphocyte ratio (NLR) have gained attention as useful tools for assessing inflammation and predicting disease prognosis. However, in Vietnam, especially among elderly patients- research on the role of NLR in monitoring and managing COPD remains limited. Therefore, we conducted the study titled: “Investigation of Neutrophil-to-Lymphocyte Ratio in Elderly Patients with Chronic Obstructive Pulmonary Disease at Thong Nhat Hospital”. To determine the NLR levels in elderly patients with COPD and evaluate the relationship between NLR and disease severity. Additionally, to compare NLR values across different patient subgroups based on factors such as age, gender, BMI, medication usage, comorbidities, and to investigate the correlation between NLR and the inflammatory marker               CRP. Sectional descriptive study conducted on elderly COPD patients visiting the respiratory outpatient clinic at Thong Nhat Hospital. From January 2025 to May 2025, we collected data from 221 elderly COPD patients. The mean age was 71 (65-77) years, Males accounted for a higher proportion than females. The mean NLR was 3,3 (2,2 – 6,2), CRP (mg/L)  4,3 (2,6 - 9,5), NLR showed a weak but statistically significant negative correlation with FEV1 (r = -0.147, p < 0,029) and a statistically significant positive correlation with CRP (r = 0,5012, p < 0,0001). Our study demonstrates that NLR is weakly but significantly inversely correlated with pulmonary function (FEV1), and positively correlated with CRP levels, indicating its potential role in assessing disease severity and inflammatory status.

Cardiac surgery patients with elevated serum procalcitonin (PCT) levels are associated with postoperative complications. The use of extracorporeal circulation is linked to an increase in PCT levels within the first 24 hours after cardiac surgery. We conducted this study with the aim of investigating serum procalcitonin levels in patients after cardiac surgery. A cross-sectional, 52 cardiac surgery patients meeting the inclusion criteria for the study. The median serum PCT level was 3.2 pg/ml. The highest value was 175 pg/ml, and the lowest was 0.03 pg/ml. Serum procalcitonin levels between the group of cardiac surgery patients with and without the use of extracorporeal circulation were 20.7 (95% CI: 9.5-31.8) and 2.8 (0.03-5.7), respectively, p=0.15. The area under the ROC curve (AUC) of 0.42 indicates poor significance when relying on serum PCT to diagnose infection. Serum procalcitonin levels are elevated in patients after cardiac surgery. An elevated PCT value alone is not sufficient evidence to diagnose infection for clinical decision-making.

The COVID-19 pandemic had a widespread impact on all aspects of human life globally, and specifically on Phu Yen Province (now part of eastern Dak Lak Province) in Vietnam. Numerous studies reported significant declines in outpatient visits, hospital admissions, and healthcare service utilization during this period. Evaluating the changes in disease patterns and healthcare service delivery at Phu Yen Traditional Medicine Hospital from 2020 to 2023 is essential for guiding service quality improvements and strengthening preparedness for future public health emergencies. To assess the variation in inpatient disease patterns and describe healthcare service activities at Phu Yen Traditional Medicine Hospital between 2020 and 2023. Study subjects included all inpatient medical records with primary ICD-10 diagnosis codes at Phu Yen Traditional Medicine Hospital from January 1, 2020 to December 31, 2023. Research design: retrospective cross-sectional descriptive study. From 2020 to 2023, musculoskeletal and neurological diseases were the most common. In 2021, COVID-19 cases appeared, with a notable rise in infectious diseases among patients under 15 (94.6%). Clinical staffing remained stable; bed numbers increased from 2022. During the pandemic, patient visits declined but clearly recovered by 2023. Bed occupancy was lowest in 2021 (69.7%) and peaked in 2023 (113.8%). The inpatient disease pattern and hospital service activity at Phu Yen Traditional Medicine Hospital were notably affected by COVID-19, with a sharp decline in 2021 followed by recovery starting in 2022.

This study aim to investigate and characterize the imaging features of knee osteoarthritis (OA) using high-field 3.0 Tesla Magnetic Resonance Imaging (MRI) in a cohort of patients at Thong Nhat Hospital. A cross-sectional descriptive study was conducted on 156 patients with radiographically confirmed knee OA who underwent 3.0T MRI between November 2024 and May 2025. Pathologies of the menisci, cruciate ligaments, collateral ligaments, subchondral bone and joint space were systematically evaluated. Univariable and multivariable logistic regression analysis was employed to identify imaging features associated with OA. The study included 156 patients (mean age 55.8±10.6 years; 73 males). The majority of patients were classified radiographically as Kellgren-Lawrence (KL) grade I (n=99, 63.46%). Despite the prevalence of early-stage radiographic disease, 3.0T MRI revealed a high burden of soft-tissue pathology. The most common ligamentous injury was a partial tear of the anterior cruciate ligament (ACL) in 42 patients (27%), while medial meniscal tears were identified in 56 patients (35.9%). Mild joint effusion was a frequent finding, present in 107 patients (68.6%). In the multivariable model, age (Odds Ratio 1.03, 95% Confidence Interval [CI] 1.02–1.04), ACL injury (OR 1.14, 95% CI 1.02–1.28), posterior cruciate ligament (PCL) injury (OR 1.24, 95% CI 1.02–1.50), collateral ligament injury (OR 1.23, 95% CI 1.02–1.49) and lateral meniscal injury (OR 1.14, 95% CI 1.00–1.29) were identified as significant independent predictors of OA. High-field 3.0T MRI is a pivotal tool for the comprehensive assessment of knee OA, detecting a wide spectrum of radiographically occult soft tissue and bone marrow pathologies. These findings, particularly those related to ligamentous and meniscal integrity, are critical to understanding the disease's biomechanical underpinnings and may be present despite minimal radiographic changes.

Hospital-acquired infections (HAIs) are a major challenge, especially in intensive care units (ICUs), where they lead to increased morbidity, mortality, prolonged stays, and higher healthcare costs. This study aimed to determine HAI rates, identify causative microorganisms, and assess associated risk factors among inpatients at Thong Nhat Hospital's ICU in 2024. A cross-sectional analysis was conducted from January to June 2024, including all eligible ICU inpatients. Data collection utilized medical records. The prevalence of HAIs was 4.9%, with the most common types being hospital-acquired pneumonia, bloodstream infections, and urinary tract infections. The primary causative agents were Gram-negative bacteria such as Acinetobacter baumannii and Pseudomonas aeruginosa. Factors associated with HAIs included age, underlying medical conditions, duration of endotracheal intubation, tracheostomy, duration of tracheostomy, urinary catheterization, duration of urinary catheter use, duration of central venous catheter use, duration of nasogastric tube placement, and length of stay in the. The HAI rate was 4.9%. Factors associated with HAIs included age, comorbidities, invasive procedures, and length of ICU-PCU stay. Strengthening infection control measures is essential to reduce HAIs and improve patient outcomes.

Decellularized vascular grafts hold potential for small-diameter vascular reconstruction owing to the ECM integrity maintained and appropriate dimensions. However, the thrombogenicity of tissue-derived grafts represents a notable limitation for clinical application. This study focuses on assessing the effectiveness of heparin immobilization on cross-linked decellularized vascular grafts prepared from porcine carotid arteries. The Layer-by-Layer (LbL) assembly technique was applied to immobilize heparin on the graft surface to improve hemocompatibility. Following LbL treatment, the grafts were examined for heparin content and surface morphology using scanning electron microscopy (SEM). To assess their potential for vascular implantation, the biomechanical properties and hemocompatibility were further evaluated. SEM observations and heparin quantification confirmed successful heparin immobilization. Biomechanical testing was measured and found to be suitable for graft applications. In terms of hemocompatibility, in vitro anticoagulant activity assessment revealed a thromboresistant surface on the luminal surface of the grafts. In addition, hemolysis rates remained within the non-hemolytic threshold as defined by ISO 10993-4. In summary, the Layer-by-Layer heparin immobilization method effectively immobilized heparin onto reinforced decellularized vascular grafts, enhanced hemocompatibility, and represents a promising approach for the development of xenogeneic vascular graft materials.

Dysphagia is increasingly recognized due to higher survival rates after central nervous system injuries, head and neck cancer treatment, and in some cases in healthy elderly individuals. It leads to severe consequences including prolonged hospitalization, delayed recovery, recurrent pneumonia, and even mortality. Bedside clinical tests alone are insufficient for diagnosis. Fiberoptic Endoscopic Evaluation of Swallowing (FEES) is one of the gold standards in dysphagia assessment, proven to be safe, effective, and feasible worldwide. However, FEES has not been widely adopted in Vietnam. This paper reports the implementation and clinical experience of FEES at the National Rehabilitation Hospital between 2019 and 2025. Literature review and clinical experience were combined. More than 700 FEES procedures were performed between April 2019 and July 2025. FEES allowed direct visualization of swallowing physiology, identification of penetration/aspiration, and guided compensatory strategies. No serious complications were reported, apart from mild discomfort. FEES is an effective and safe diagnostic tool for dysphagia, supporting individualized management strategies and should be expanded in Vietnam.

Cancer is an increasing health burden, particularly among older adults [14]. Palliative care (PC) plays a crucial role in improving patients’ quality of life. This study aimed to identify palliative care needs and associated factors among cancer patients at the Central Highlands Regional General Hospital in 2024. Subjects and Methods: A cross-sectional descriptive study was conducted among 434 cancer patients aged ≥18 years hospitalized from January to September 2024. Data were collected through face-to-face interviews using a structured questionnaire. Statistical analysis was performed using SPSS 20.0 with multivariate logistic regression. Results: 88.2% of patients had palliative care needs. The highest needs included communication & social relationships (83.9%), physical support (81.8%), and psychological support (73.5%). Factors associated with higher needs included female gender (OR=3.21; p=0.001), rural residence (OR=2.61; p=0.004), unemployment/retirement (OR=3.07; p=0.001), metastatic cancer (OR=2.87; p=0.004), and presence of complications (OR=2.45; p=0.012). Conclusion: Most cancer patients, particularly older adults, have diverse palliative care needs. Integrating geriatric considerations into palliative care is essential to address physical, psychological, and social needs comprehensively, thereby improving quality of life and reducing healthcare burden.

To assess the clinical effectiveness of 3D-printed models in minimally invasive plate osteosynthesis (MIPO) for ankle fractures, compared with conventional surgical planning. Methods: A quasi-experimental study was conducted at Thong Nhat Hospital from January 2024 to January 2025. Twenty-eight patients with ankle fractures were enrolled and divided equally into two groups (n = 14 each): one managed with 3D-assisted preoperative planning and the other with conventional methods. Results: The 3D-assisted group demonstrated significantly better intraoperative and postoperative outcomes. Mean operative time was shorter (55.3 ± 6.6 vs. 68.1 ± 5.3 minutes, p = 0.001), blood loss was lower (75.5 ± 10.2 vs. 110.3 ± 15.7 ml, p < 0.001), and C-arm exposure was reduced (10.8 ± 1.1 vs. 17.2 ± 1.5 shots, p = 0.003). Functional recovery was superior, with higher Rasmussen scores at 3 months (26.7 ± 1.3 vs. 23.4 ± 2.1, p = 0.002). Postoperative complications were also less frequent in the 3D group. Conclusion: Preoperative 3D printing significantly enhanced surgical accuracy and clinical outcomes in ankle fracture management. Patients treated with 3D assistance experienced shorter operations, reduced intraoperative blood loss, fewer fluoroscopic exposures, improved functional recovery, and a lower complication rate.

Open tibial shaft fractures are common injuries, accounting for the highest proportion of open long bone fractures. External fixation, particularly the FESSA frame, is highly valued for its safety, ease of application, and convenience in soft tissue wound care. To evaluate the outcomes of treating open tibial shaft fractures using the FESSA external fixation system at Thong Nhat Hospital. A retrospective cross-sectional study was conducted on 53 patients with open tibial shaft fractures treated with the FESSA frame. Bone healing was assessed using the RUST scoring system, and functional recovery was evaluated using the Karlström-Olerud criteria. The bone union rate was 92.3%, with an average healing time of 6.75 ± 3.44 months. Good and excellent functional recovery outcomes accounted for 87.5%. The FESSA external fixation system is an effective method for managing open tibial shaft fractures.

Evaluation of the analgesic effect of low-power intravascular laser combined with electroacupuncture compared to electroacupuncture alone in patients with chronic low back pain treated at the Traditional Medicine Department of Thong Nhat Hospital. 60 patients with confirmed diagnosis of chronic back pain at the Department of Traditional Medicine, Thong Nhat Hospital. Patients were randomly divided into 2 groups. The control group (n=30) was treated with electroacupuncture; the intervention group (n=30) was treated with low-power intravascular laser combined with electroacupuncture similar to the control group. The treatment course was continuous for 10 days, once a day. Treatment effectiveness was assessed based on the VAS pain scale assessed after 5 and 10 days of treatment. After 10 days of treatment, the VAS pain score was 2,42 ± 1,67 in the control group and 1,57 ± 1,48 in the intervention group. Both groups experienced a reduction in pain to the levels of no pain (0–2 points) or mild pain (2–4 points). The intervention group demonstrated superior pain relief starting from day 5, reaching statistical significance by day 10 (p = 0.03 < 0.05). Combining electroacupuncture with intravascular low-level laser therapy  enhance effeciency in relive pain due to lumbago. No significant side effects were noted.

To evaluate the treatment outcomes of using radiofrequency ablation for chronic lumbar facet joint pain. This was a non randomized, interventional study conducted on patients with chronic lumbar facet joint pain who were treated with radiofrequency ablation at the Department of Neurosurgery, Thong Nhat Hospital, Ho Chi Minh City, from September 2024 to April 2025. We included 15 patients who met the study criteria. The mean VAS scores after the intervention at 1 week, 1 month, and 3 months were 3.4 ± 1.05; 1.7 ± 1.1; and 1.4 ± 0.91, respectively. The application of radiofrequency ablation for treating chronic lumbar facet joint pain is a method that initially shows effectiveness and safety.

Stroke is the leading cause of severe disability among adults worldwide. In Vietnam, the burden is rising rapidly. The increasing incidence drives higher healthcare costs, reduced work capacity, and greater social pressures. Accordingly, post-stroke motor rehabilitation is a priority to reduce mortality and complications and limit disability. At Thống Nhất Hospital, physiotherapy combined with electroacupuncture has been used for years under the guidance of the Ministry of Health, with observed functional benefits. Still, its effectiveness has not been formally evaluated. This study aimed to generate evidence to guide regimen selection and optimise patient outcomes. Materials and Methods: A clinical interventional study without a control group was conducted, employing a pre- and post-treatment comparison. Eighty-six patients newly diagnosed with stroke within the preceding three months, receiving inpatient or outpatient care at the Departments of Rehabilitation, Emergency Interventional Cardiology, Neurology, and Traditional Medicine at Thống Nhất Hospital from January to October 2025, were included. Motor function recovery was assessed through manual muscle testing and the Barthel Index after 30 days of treatment. Results: The proportion with muscle strength grades 0–2 fell from 53.49% to 17.44%, whereas grades 4–5 rose from 29.07% to 59.30%. The mean Barthel Index increased from 44.24 ± 18.16 to 69.07 ± 17.90. Post-intervention classifications were completely independent, 12.79%; partially dependent, 76.74%; entirely dependent, 10.47%. Conclusion: Physiotherapy plus electroacupuncture appears safe and effective for post-stroke rehabilitation, improving muscle strength and independence in activities of daily living. Benefits extend beyond statistical significance to practical gains in quality of life and community reintegration.

Osteoporotic vertebral compression fractures are a major cause of back pain and reduced spinal function in elderly patients. To evaluate the pain-relieving effectiveness of vertebroplasty in patients with osteoporotic vertebral compression fractures. A prospective study was conducted on 26 patients, assessing VAS, Macnab, and ODI scores before and after cement vertebroplasty, analyzed according to the number of fractured vertebrae. VAS scores significantly decreased from 4.85 ± 0.61 to 1.81 ± 0.49 after the procedure (p < 0.001). Macnab and ODI scores also improved markedly, with pain relief observed even in patients with multiple fractured vertebrae. Vertebroplasty is a minimally invasive procedure that effectively reduces pain and improves spinal function in patients with one or multiple osteoporotic vertebral fractures.

46 patients (patients) with proximal humerus fractures were operated on at Thong Nhat Hospital from January 2019 to April 2024. They were divided into 2 groups, group 1: 22 patients with the support of 3D printing models and group 2: 24 patients without 3D models. All patients were open reduction and internal fixation with a locking plate on the proximal humerus. The patients were evaluated for bone healing and deformity on X-ray, and shoulder function was assessed according to the Constant scale. Surgical time of group 1 (90.68 ± 13.029) was shorter than group 2 (105.25 ± 12.037). Mean blood loss of group 1 (164.55 ± 50.042) was less than group 2 (218.75 ± 28.789). Shoulder function were very good and good, accounting for a high rate of 82.6%, and there was no difference between the 2 groups. Postoperative complications had a low rate and there was no difference between the 2 groups in wound surface infection and subacromial conflict. Complications of screw perforation, osteomyelitis, and bone nonunion have not been observed.

Melanin overproduction can lead to hyperpigmentation issues such as freckles and melasma, impacting aesthetics and health. This study investigates the inhibitory effects of C-Phycocyanin (C-PC) extracted from Spirulina on melanin synthesis using a zebrafish (Danio rerio) model. C-PC demonstrated significant tyrosinase inhibition and reduced melanin content in zebrafish embryos in a dosedependent manner. The IC50 value of C PC for tyrosinase inhibition was determined to be 38.36 ± 19 µg/mL. At the highest tested concentration (10 µg/mL), C-PC reduced melanin content in zebrafish embryos by approximately 48.57%, compared to 71.08% inhibition observed with kojic acid. Importantly, C-PC exhibited low toxicity, with treated embryos maintaining normal morphology and viability. The findings suggest the potential application of C-PC as a natural depigmenting agent in cosmetic formulations.

To evaluate the safety and mid-term outcomes of laparoscopic right hemicolectomy in elderly patients (≥65 years old). A retrospective descriptive study was conducted on 52 patients aged ≥65 years who underwent laparoscopic radical right hemicolectomy with lymph node dissection at Thong Nhat Hospital from 01/2020 to 01/2025. Data analysis was performed using SPSS software version 25.0. The early complication rate was 15.4%, and the 30-day mortality rate was 1.9%. The median number of harvested lymph nodes was 13.2 (92.3% of patients had ≥12 nodes). The 36-month disease-free survival (DFS) and overall survival (OS) rates were 62.5% and 68.9%, respectively. Only 55.6% of indicated patients completed the adjuvant chemotherapy regimen. Laparoscopic right hemicolectomy is a safe, feasible, and oncologically sound procedure for elderly patients. The mid-term survival outcomes were impacted by a low adjuvant chemotherapy completion rate.

Autologous Platelet-Rich Plasma (PRP) is an increasingly popular biological therapy in sports medicine and rehabilitation, particularly for periarticular soft tissue pathologies of the shoulder. To evaluate the clinical efficacy of autologous PRP in treating simple shoulder periarthritis over a 4-month follow-up period and to analyze factors associated with treatment outcomes. Methods: A longitudinal clinical intervention study was conducted on 30 patients diagnosed with simple shoulder periarthritis. After 4 months, the mean Visual Analogue Scale (VAS) score significantly decreased from 5.6 to 2.6, accompanied by improvements in ultrasonographic findings. Greater pain reduction was observed in younger patients. Adverse effects were primarily limited to mild, self-limiting injection-site pain resolving within 3 days. Autologous PRP is a safe and effective treatment for shoulder periarthritis, especially in younger populations.

To evaluate the clinical features, paraclinical findings, and treatment outcomes of giant cell tumor (GCT) of bone. Fifteen patients aged 20 to 40 years with bone lesions underwent surgery and histopathological examination and were diagnosed with “giant cell tumor of bone” between January 2011 and December 2024. There were 6 males and 9 females. The most common tumor location was the tibia (53.3%). The most frequent histological pattern was fibrosis, present in 11 cases (73.3%). The average follow-up duration was 55 months. Local recurrence occurred in 3 out of 15 cases, with no cases of metastasis. The GCT cases in our study shared pathological characteristics with classic GCT populations. No specific histological feature was associated with adverse outcomes. Curettage combined with bone cement filling proved to be an effective treatment option.

Non-variceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency requiring early risk stratification to improve prognosis. This study aimed to evaluate the value of the Glasgow-Blatchford Score (GBS) in prognosticating patients with NVUGIB. This prospective, descriptive study included patients diagnosed with NVUGIB admitted to the Emergency Department of Thong Nhat Hospital from January 2020 to July 2020. Among 122 patients (73.0% male, mean age 63 years), 45.9% required medical intervention (MI), 5.7% experienced re-bleeding, and 2.5% died. The mean GBS was 9. The GBS (AUC=0.828) showed better prognostic value for MI than the clinical Rockall score (AUC=0.650). With a cut-off score of ≥10, the GBS had a sensitivity of 0.68 and a specificity of 0.88 in predicting the need for MI. Most patients with NVUGIB were elderly. The GBS is a valuable tool for prognosticating the need for medical intervention in this patient group.

To evaluate the effectiveness of early mobilization on patients after gastrointestinal surgery. This is a cross-sectional study observed on 78 patients who underwent gastrointestinal tumor surgery at the Department of Gastrointestinal Surgery, Thong Nhat Hospital, from October 2024 to June 2025. We collected and analyzed data on age, sex, time to first flatus, Visual Analog Scale (VAS) pain scores, Timed Up and Go test performance, postoperative complications, and time to discharge. Physiotherapy was typically initiated two days postoperatively and combined respiratory with mobility training. Patients who achieved early mobilisation demonstrated earlier return of bowel function, shorter hospital stay, lower VAS pain scores, and better functional mobility as indicated by shorter Timed Up and Go test durations at postoperative days 1, 3, and 7 compared with those without early mobilization. The study demonstrated that the early mobilization group had an earlier time to first flatus, shorter length of hospital stay, lower pain levels, and better functional mobility compared with the non-early mobilization group.