Research

To survey the prevalence of cancer types, disease stages, and treatment methods in Department A1, Thong Nhat Hospital, from 2019 to 2023, and to evaluate initial cancer treatment outcomes. A cross-sectional descriptive study was conducted on 192 cancer patients admitted for inpatient and outpatient treatment in Department A1 from January 2019 to December 2023. Prostate cancer (29.2%) and colorectal cancer (22.4%) were the most common types. In terms of treatment, 68.2% of patients received two or more treatment modalities, with surgery and chemotherapy being the most frequently applied methods. The proportion of patients receiving late treatment (stage III-IV) was low (11.5%), with 52.6% of patients stable after treatment and a mortality rate of 20.8%. The study highlights the highest prevalence in prostate and colorectal cancer. Multimodal treatment plays a crucial role in stabilizing patients, with a low rate of late treatment and positive treatment outcomes.

To investigate the correlation between triglyceride, lipase, C-reactive protein (CRP), and white blood cell (WBC) levels in patients with acute pancreatitis (AP) upon hospital admission. A cross-sectional analytical study was conducted involving 222 patients admitted to Thong Nhat Hospital between January 2023 and March 2025. Data on triglyceride, lipase, CRP, WBC levels were collected at the time of admission. Among AP patients, 68% had elevated triglyceride levels. Specifically, 30% had moderately elevated triglycerides, while 28% had severely or very severely elevated levels. The distribution of study indicators was wide. A weak negative correlation was found between lipase - triglyceride levels, and between lipase and CRP levels (p < 0,001). No significant correlation was observed between lipase and WBC levels, or between WBC and triglyceride levels at the time of admission. At the time of admission, 28% of AP patients had severe or very severe hypertriglyceridemia. Lipase levels showed a weak negative correlation with triglyceride and CRP levels. These findings suggest that triglyceride levels may be a useful marker for assessing the severity of AP.

To determine the prevalence of coagulopathy in sepsis patients, clinical indicators according to the SOFA score, and laboratory indicators based on the SIC score at Thong Nhat Hospital. To investigate the correlation between the SIC score and disseminated intravascular coagulation (DIC). A cross-sectional descriptive study of sepsis patients aged 18 and older at Thong Nhat Hospital based on the Sepsis-3 criteria from November 2023 to July 2024. Among 106 sepsis patients, 69 (65.1%) were male, with an average age of 69.9 ± 17.1 years. The majority had hypertension (41.5%) and diabetes (26.4%), with infection sources primarily from the respiratory system (44.3%) and gastrointestinal tract (21.7%). The median SOFA score and SOFA (SIC score) were 5 (3 – 7) and 3 (2 – 5), respectively. Multiorgan dysfunction syndrome (MODS) was present in 54.7% of patients. The prevalence of coagulopathy in sepsis patients according to the SIC score was 49.1%. There was a statistically significant difference in the rate of coagulopathy between the multiorgan dysfunction syndrome group, those with thrombocytopenia < 150 G/L; INR > 1.2; aPTT > 37s; D-Dimer > 500ng/ml; total bilirubin > 21µmol/L; Hb < 10.5g/dL (p < 0.05). A positive correlation of r = 0.6 was found between the SIC score and the Overt-DIC score, significant with p < 0.05. Most sepsis patients are elderly with comorbidities. The rate of coagulopathy due to sepsis according to the SIC score is high and correlates with laboratory indicators such as thrombocytopenia, INR, aPTT, D-Dimer, total bilirubin, and Hb. There is a strong positive correlation with the DIC score.

Albuminuria is a key marker for early kidney damage and cardiovascular risk in patients with diabetes and hypertension, even when glomerular filtration rate (GFR) is preserved. However, data on the prevalence of albuminuria in Vietnamese populations remains limited. To assess the prevalence of albuminuria and its associated clinical factors in patients with type 2 diabetes and/or hypertension. This cross-sectional study included 209 patients at Thong Nhat Hospital, Ho Chi Minh City. Clinical characteristics, blood pressure control, and laboratory data including urinary albumin-to-creatinine ratio (UACR) were collected. Albuminuria was defined as UACR ≥30 mg/g, including microalbuminuria (30–299 mg/g) and macroalbuminuria (≥300 mg/g). Logistic regression was used to identify factors associated with albuminuria. The mean age was 68.04 ± 13.94 years, and 38.8% had type 2 diabetes. Overall, 27.7% of patients had albuminuria, including 16.7% with microalbuminuria and 11.0% with macroalbuminuria. Blood pressure was controlled in 58.7% of participants. Only 42.5% of diabetic patients achieved glycemic targets. Macroalbuminuria was significantly more common in patients with uncontrolled blood pressure (18.6% vs. 5.7%, p < 0.01). No significant associations were found between albuminuria and age, sex, or ASCVD. Albuminuria is prevalent in patients with diabetes and hypertension, particularly among those with uncontrolled blood pressure. These findings support routine screening for albuminuria and early initiation of renoprotective therapy to prevent renal and cardiovascular complications in high-risk Vietnamese populations.

Blood transfusion plays a crucial role in the treatment of various acute and chronic conditions, especially in elderly patients with comorbidities requiring transfusion interventions. Understanding the correlation between the demand for blood products and the disease patterns can help hospitals proactively develop plans for blood storage and distribution, optimizing treatment and minimizing the risks of shortages or delays.: To determine the correlation between the demand for blood products and the disease patterns in first-time blood transfusion patients at Thong Nhat Hospital in 2023. A retrospective cross-sectional study was conducted, analyzing the types and quantities of blood products from blood transfusion requests for 2,180 patients who underwent their first blood transfusion. The highest proportion of patients were diagnosed with anemia (25.83%), followed by gastrointestinal bleeding (19.68%) and cancer (12.52%). Red blood cell concentrates (RBC) were the most commonly used blood products, particularly for anemia (88.45%), gastrointestinal bleeding (93.24%), and cancer (93.04%) patients. Fresh frozen plasma (FFP) was predominantly used in gastrointestinal bleeding patients (4.90%), with a high average quantity (5.29 units per patient). Platelet concentrates (PC) were mainly used in anemia (9.24%) and cancer (5.86%) patients. All results demonstrated statistically significant differences in the demand for blood products based on disease type (p < 0.001). The demand for blood products is closely correlated with the disease patterns in first-time blood transfusion patients at Thong Nhat Hospital. Red blood cell concentrates are the primary blood product used in anemia, gastrointestinal bleeding, and cancer patients. The distribution of blood product usage reflects the disease characteristics of each group and serves as a critical basis for developing blood inventory and transfusion plans to ensure efficient and appropriate blood use in hospitals.

Survey compliance with the 1-hour sepsis bundle in patients with sepsis and septic shock at Thong Nhat hospital and analyze the relation between compliance with the 1-hour bundle and patient’s outcomes. A retrospective study was conducted on 55 patients admitted to the Emergency Department of Thong Nhat Hospital from January 2024 to July 2024. Patients were selected based on the diagnostic criteria for sepsis in Sepsis-3 definition with no prior treatment. Compliance with the 1-hour sepsis bundle was assessed, including blood culture collection, initiation of antibiotics, fluid resuscitation, lactate measurement, and vasopressor administration when needed. In 55 patients included in the study, male accounted for 50.1%; proportion of female was 49.1% with mean age was 79 ± 18.35. According ro the diagnosis of emergency doctors, there were 43/55 (78.2%) cases of sepsis and 12/55 (21.8%) cases of septic shock. The history of hypertension was the majority (65.5%) with the most common focus of infection being the respiratory tract (54.5%), urinary tract (30.9%), of which 14 cases had 2 or more foci of infection. Regarding compliance with the one-hour bundle in the care of patients with sepsis and septic shock, 35/55 (63.6%) completed the one-hour package and 25.4% did not complete it. Adherence to the one-hour bundle in primary analyses showed improved mortality in patients with sepsis and septic shock with OR = 5.07 (p < 0.05). Our study showed that proportion of one-hour bundle compliance had improved over time, with increasing clinical application. It also demonstrated the effectiveness and importance of adherence to the one-hour bundle in improving sepsis and septic shock patient survival.

Colonoscopy is an important procedure for diagnosing and treating lower gastrointestinal diseases. However, performing colonoscopy in very elderly patients poses many challenges, particularly in the quality of bowel preparation and the risk of complications. Objective: To describe the characteristics of colonoscopy in patients aged ≥ 80. Methods: A cross-sectional study was conducted on 254 patients aged ≥ 80 who underwent colonoscopy at Thong Nhat Hospital. Results: The mean age was 84,7 ± 3,16. No cases of perforation or bleeding related to colonoscopy were reported. 32,7% procedures were performed with sedation. The main reasons for incomplete colonoscopies were poor bowel preparation (52,6%) and intolerable pain (39,5%). Polyps were the most commonly detected lesions (48,6%), with the majority having ≥ 3 polyps and measuring <10mm. Notably, colorectal cancer was found in 6,7% of cases. Most polyps and colorectal cancers were located in the left colon. Conclusion: Colonoscopy in very elderly patients is safe, but the risks and benefits should be carefully weighed before performing the procedure.

Major adverse cardiovascular events (MACE) encompass serious complications that significantly impact the prognosis and quality of life in patients with acute myocardial infarction (AMI). Despite their clinical relevance, real-world data on short-term MACE in Vietnamese settings—particularly at Thong Nhat Hospital—remain limited. This study aims to determine the incidence of MACE during hospitalization and within 30 days post-admission among patients with AMI treated at Thong Nhat Hospital. A prospective cohort study was conducted on 259 patients diagnosed with AMI and admitted to the Emergency-Intervention Cardiology Department of Thong Nhat Hospital from October 2023 to June 2024. MACE was defined as a composite of all-cause mortality, cardiogenic shock, recurrent myocardial infarction, acute heart failure, and life-threatening ventricular arrhythmias. The in-hospital MACE rate was 26.64% (69/259), with acute heart failure being the most frequent event (16.22%), followed by cardiogenic shock (5.41%), all-cause mortality (4.63%), life-threatening ventricular arrhythmias (3.86%), and recurrent myocardial infarction (1.93%). At 30 days, the cumulative MACE rate increased to 33.59% (87/259), with acute heart failure continuing to predominate (23.17%). The short-term incidence of MACE in patients with AMI at Thong Nhat Hospital remains substantial, particularly due to acute heart failure. These findings underscore the need for early risk stratification, intensive monitoring, and optimized, multimodal management strategies during the acute phase to improve clinical outcomes and reduce cardiovascular complications.

This study investigates the distribution of pathogenic microorganisms and their antibiotic resistance status in bloodstream infections at Thong Nhat Hospital from April 30, 2024, to May 1, 2025. Retrospective, cross-sectional descriptive study conducted on 770 microbial isolates obtained from blood samples from April 30, 2024, to May 1, 2025, at Thong Nhat Hospital. Among the total 770 isolated strains, bacteria accounted for 97.27%, and fungi accounted for 2.73%. The common pathogens included Coagulase-negative Staphylococci (30.44%), Escherichia coli (21.23%), Staphylococcus aureus (8.54%), Klebsiella pneumoniae (7.34%), and Pseudomonas aeruginosa (2.94%). E. coli showed >80% susceptibility to amikacin and piperacillin/tazobactam and >97% susceptibility to carbapenems. K. pneumoniae demonstrated resistance rates of 30.2% to imipenem, 31,3% to meropenem, and 25.5% to ertapenem. P. aeruginosa resistance rates were 50% to imipenem and 40.9% to meropenem. S. aureus exhibited high resistance to benzylpenicillin (96.6%), erythromycin (75.9%), and clindamycin (67.2%) but remained 100% susceptible to vancomycin, linezolid, teicoplanin, and tigecycline. The MRSA rate was 62.5%. Candida spp. remained susceptible to commonly used antifungal agents. Bacteria are the primary cause of bloodstream infections. Multidrug-resistant strains such as P. aeruginosa, K. pneumoniae, and MRSA account for a significant proportion. Continuous monitoring of resistance patterns supports clinicians in selecting appropriate antibiotics, thereby reducing mortality and treatment costs.

Early vascular recanalization in acute ischemic stroke is an effective therapeutic strategy for neurological recovery; however, the outcome is influenced by various patient-related and baseline factors. To evaluate the effectiveness of recanalization therapy and investigate factors associated with neurological improvement in patients with acute ischemic stroke. A retrospective descriptive study was conducted on 186 acute ischemic stroke patients treated at Thong Nhat Hospital from January 2024 to March 2025. Clinical assessments (NIHSS, mRS), degree of recanalization (TICI), and associated factors were analyzed. The proportion of patients with NIHSS improvement ≥4 points was high in the thrombectomy-only and bridging therapy groups, at 80,7% and 90,3%, respectively. The highest rate of complete recanalization (TICI 3) was observed in the bridging therapy group (64,5%). The highest proportion of favorable functional outcome at discharge (mRS 0–2) was seen in the IV thrombolysis-only group (80,6%). Factors significantly associated with neurological improvement included: baseline mRS 0–2 (p=0,016), pre-intervention blood pressure (p<0,05), initial NIHSS score (p=0,004), pre-intervention blood glucose level (p=0,003), degree of recanalization (p=0,048), and hemorrhagic transformation (p=0,001). Combined intravenous thrombolysis and mechanical thrombectomy yielded the greatest neurological improvement. Multiple baseline factors are predictive of prognosis and should be thoroughly assessed prior to intervention.

Laparoscopic surgery (LS) is increasingly applied in the placement and salvage of Tenckhoff catheters for peritoneal dialysis in end-stage chronic kidney disease (ESKD). This study aims to evaluate the preliminary efficacy and safety of this technique. A retrospective descriptive study was conducted on 27 patients who underwent laparoscopic Tenckhoff catheter placement or salvage at Thong Nhat Hospital from January 2022 to October 2024. There were 17 new catheter placements (60.71%) and 11 salvages (39.29%). The mean age was 56 ± 17 years, and the average operative time was 60.59 ± 17.09 minutes. In the placement group, 29.41% underwent omentectomy, 17.64% received omentopexy, and 58.82% had catheter fixation to the abdominal wall. Reported complications included poor outflow and abdominal wall hernia (11.76%), and infection (5.88%). In the salvage group, 81.82% had catheter migration due to the omentum, with 54.55% requiring omentectomy and 18.18% undergoing omentopexy; all patients had catheter fixation. Complications included poor outflow and hernia (9.09%), with no infections or catheter removals observed within 3 months. Catheter function was well maintained postoperatively. Laparoscopic surgery is a safe and effective method for Tenckhoff catheter placement and salvage, supporting longterm catheter function and reducing risks of infection and obstruction. It is a viable option for renal replacement therapy with peritoneal dialysis in ESKD patients.

Population aging is an inevitable global trend, driven by increased life expectancy and a prolonged decline in the total fertility rate (TFR) below replacement level. This article analyzes the current situation and underlying causes of persistently low fertility in high-income countries and in Vietnam. It points out that once the TFR drops below 2.1 for several decades, almost no country has succeeded in restoring replacement-level fertility, despite implementing numerous supportive policies at great cost. Through the analysis of demographic, economic, and social data from over 40 countries, combined with typical surveys conducted in Ho Chi Minh City and Japan, the author identifies five root causes of fertility decline. Based on these insights, a comprehensive system of solutions is proposed to shift from unsustainable to sustainable aging. Key measures include: ensuring a living wage for a family of four; reforming the social insurance system; expanding public housing and preschool education; promoting gender equality; preserving Vietnamese cultural traditions that value family life; educating citizens on knowledge and skills for building happy families; raising awareness of civic responsibility; and creating a social environment that is friendly to women and children.The article emphasizes that without decisive policy changes during the 2025–2050 period, Vietnam’s population could shrink from a peak of 107 million in 2050 to just 88 million by 2100, with further severe decline thereafter. Conversely, if strategic solutions are comprehensively implemented, Vietnam can fully achieve the goal: happy elderly, a prosperous nation, and a thriving people.

Pheochromocytoma is a rare endocrine cause of secondary hypertension. The definitive diagnosis requires a combination of biochemical testing and imaging studies. Management of pheochromocytoma-induced hypertension involves appropriate pharmacologic therapy followed by surgical resection of the adrenal tumor. In this report, we present the case of an elderly patient who was admitted with chest pain and initially diagnosed with acute coronary syndrome. However, invasive coronary angiography revealed no significant stenosis. Subsequent investigations confirmed the diagnosis of pheochromocytoma. The patient underwent successful medical stabilization and surgical removal of the tumor. This case highlights the importance of multidisciplinary collaboration in the diagnosis and treatment of pheochromocytoma at Thong Nhat Hospital.

Periprosthetic fractures around the knee are serious complications following total knee arthroplasty, commonly occurring in elderly patients with poor bone quality. The most frequent fracture site is the supracondylar region of the femur, followed by the tibia and patella. Causes may include low-energy trauma, suboptimal surgical technique, or implant loosening. Diagnosis and treatment of periprosthetic fractures around the knee are challenging due to interference from the implant and compromised bone quality. Treatment may be conservative in non-displaced fractures or surgical in cases of displacement, implant loosening, or comminuted fractures. Surgical options include locked plating, retrograde intramedullary nailing, or revision arthroplasty using long-stem components. Fracture classifications by Lewis-Rorabeck and Su are helpful in guiding management. Tibial and patellar periprosthetic fractures may also occur and require careful preoperative planning to avoid complications. Postoperative complications such as non-union, infection, or soft tissue injury are common when not properly managed. Prevention through patient screening, improved surgical technique, and close postoperative monitoring plays a critical role in reducing fracture incidence. Successful treatment requires a multidisciplinary approach involving orthopedic surgery, rehabilitation, and management of comorbidities.

Periprosthetic fractures of the hip are serious complications following total hip arthroplasty, particularly affecting elderly patients, those with osteoporosis, or individuals with a history of revision surgeries. These fractures may occur intraoperatively or postoperatively, involving the femoral shaft (classified as Vancouver A, B, or C) or the acetabulum (Paprosky classification). Acetabular fractures are less common than femoral fractures. The mechanisms of fracture involve both biological factors (such as stress risers, implant loosening, and poor bone quality) and external forces (such as falls, torsional, and bending loads). Identified risk factors include advanced age, female gender, osteoporosis, implant loosening, use of cementless femoral stems, rheumatoid arthritis, and multiple revision surgeries. Studies have reported the incidence of periprosthetic fractures after primary hip replacement ranging from 0.8% to 4.5%, with higher rates observed following revision procedures. Diagnosis relies on both clinical and paraclinical assessments, with plain radiographs and computed tomography (CT) being the primary tools to evaluate implant stability, bone loss, and to guide treatment planning. Treatment depends on the type of fracture and the stability of the prosthesis. Stable Vancouver A fractures may be managed conservatively; Vancouver B1 fractures often require internal fixation with plates and screws; B2 and B3 fractures typically necessitate revision with a long-stem prosthesis and bone grafting if needed. Nondisplaced acetabular fissure fractures may be treated conservatively, but displaced or unstable fractures require surgical reconstruction using plates, screws, bone grafts, or specialized acetabular components. Prognosis is influenced by patient age, the severity of osteoporosis, prosthesis stability, and the number of prior surgeries. The mortality rate following periprosthetic hip fractures ranges from 7% to 18% within the first year postoperatively. Prevention, thorough risk assessment, and appropriate treatment strategies play crucial roles in improving clinical outcomes.

Osteoporosis is a common complication in elderly patients with chronic kidney disease (CKD), particularly at fracture-prone sites such as the femoral neck. However, osteoporosis screening in this population remains insufficient in routine clinical practice, especially in Vietnam. This study aimed to determine the prevalence of osteoporosis and its associated factors in patients aged ≥70 years with CKD. A cross-sectional study was conducted on 76 patients aged ≥70 years with stage 3–5 CKD (including 47 predialysis and 29 maintenance hemodialysis patients) at Thong Nhat Hospital from September 2022 to June 2024. Clinical and laboratory data were collected, and bone mineral density (BMD) was measured using DXA at three sites: lumbar spine (LS), total hip (TH), and femoral neck (FN). Logistic regression was used to identify predictors of osteoporosis, with model accuracy evaluated by AUC. The overall prevalence of osteoporosis was 43.4%, highest at the femoral neck (40.8%). Mean BMD at the femoral neck (0.559 ± 0.147 g/cm²) was significantly lower than at the total hip (0.713 ± 0.168) and lumbar spine (0.901 ± 0.209; p < 0.001). Independent protective factors included male sex (OR = 0.082; p < 0.001) and higher BMI (OR = 0.670; p = 0.004). Maintenance hemodialysis was identified as an independent risk factor (OR = 4.368; p = 0.027). The predictive model incorporating these three variables achieved good accuracy (AUC = 0.89). Patients aged ≥70 years with CKD—particularly women, those with low BMI, and those on maintenance hemodialysis—are at high risk of osteoporosis, especially at the femoral neck. Routine BMD screening should be implemented for early detection and timely intervention.

 Laparoscopic restoration of intestinal continuity after Hartmann’s procedure offers significant benefits but remains a considerable challenge for gastrointestinal surgeons. To evaluate the feasibility, safety, and efficacy of laparoscopic colostomy closure after Hartmann’s procedure at Thong Nhat Hospital. A retrospective descriptive analysis was conducted on 35 cases from February 2017 to May 2025. Patients who had undergone Hartmann’s procedure with an end colostomy and received laparoscopic intestinal continuity restoration were included. The laparoscopic success rate was 85.71%. Major complications included surgical site infection (30%), anastomotic leakage, and intestinal obstruction (3% each). The average operative time was 162 minutes, and the mean hospital stay was 9.3 days. There were no mortality cases. Laparoscopic reversal of Hartmann’s procedure is a feasible, safe, and effective method with a high success rate and low complication rate.

Chronic Obstructive Pulmonary Disease (COPD) is one of the leading causes of mortality and disability worldwide. Among elderly patients, COPD not only reduces quality of life but also places a significant burden on healthcare systems. Chronic inflammation plays a key role in the pathogenesis of COPD. In recent years, peripheral blood inflammatory markers such as the neutrophil-to-lymphocyte ratio (NLR) have gained attention as useful tools for assessing inflammation and predicting disease prognosis. However, in Vietnam, especially among elderly patients- research on the role of NLR in monitoring and managing COPD remains limited. Therefore, we conducted the study titled: “Investigation of Neutrophil-to-Lymphocyte Ratio in Elderly Patients with Chronic Obstructive Pulmonary Disease at Thong Nhat Hospital”. To determine the NLR levels in elderly patients with COPD and evaluate the relationship between NLR and disease severity. Additionally, to compare NLR values across different patient subgroups based on factors such as age, gender, BMI, medication usage, comorbidities, and to investigate the correlation between NLR and the inflammatory marker               CRP. Sectional descriptive study conducted on elderly COPD patients visiting the respiratory outpatient clinic at Thong Nhat Hospital. From January 2025 to May 2025, we collected data from 221 elderly COPD patients. The mean age was 71 (65-77) years, Males accounted for a higher proportion than females. The mean NLR was 3,3 (2,2 – 6,2), CRP (mg/L)  4,3 (2,6 - 9,5), NLR showed a weak but statistically significant negative correlation with FEV1 (r = -0.147, p < 0,029) and a statistically significant positive correlation with CRP (r = 0,5012, p < 0,0001). Our study demonstrates that NLR is weakly but significantly inversely correlated with pulmonary function (FEV1), and positively correlated with CRP levels, indicating its potential role in assessing disease severity and inflammatory status.

Cardiac surgery patients with elevated serum procalcitonin (PCT) levels are associated with postoperative complications. The use of extracorporeal circulation is linked to an increase in PCT levels within the first 24 hours after cardiac surgery. We conducted this study with the aim of investigating serum procalcitonin levels in patients after cardiac surgery. A cross-sectional, 52 cardiac surgery patients meeting the inclusion criteria for the study. The median serum PCT level was 3.2 pg/ml. The highest value was 175 pg/ml, and the lowest was 0.03 pg/ml. Serum procalcitonin levels between the group of cardiac surgery patients with and without the use of extracorporeal circulation were 20.7 (95% CI: 9.5-31.8) and 2.8 (0.03-5.7), respectively, p=0.15. The area under the ROC curve (AUC) of 0.42 indicates poor significance when relying on serum PCT to diagnose infection. Serum procalcitonin levels are elevated in patients after cardiac surgery. An elevated PCT value alone is not sufficient evidence to diagnose infection for clinical decision-making.

Hospital-acquired infections (HAIs) are a major challenge, especially in intensive care units (ICUs), where they lead to increased morbidity, mortality, prolonged stays, and higher healthcare costs. This study aimed to determine HAI rates, identify causative microorganisms, and assess associated risk factors among inpatients at Thong Nhat Hospital's ICU in 2024. A cross-sectional analysis was conducted from January to June 2024, including all eligible ICU inpatients. Data collection utilized medical records. The prevalence of HAIs was 4.9%, with the most common types being hospital-acquired pneumonia, bloodstream infections, and urinary tract infections. The primary causative agents were Gram-negative bacteria such as Acinetobacter baumannii and Pseudomonas aeruginosa. Factors associated with HAIs included age, underlying medical conditions, duration of endotracheal intubation, tracheostomy, duration of tracheostomy, urinary catheterization, duration of urinary catheter use, duration of central venous catheter use, duration of nasogastric tube placement, and length of stay in the. The HAI rate was 4.9%. Factors associated with HAIs included age, comorbidities, invasive procedures, and length of ICU-PCU stay. Strengthening infection control measures is essential to reduce HAIs and improve patient outcomes.

Open tibial shaft fractures are common injuries, accounting for the highest proportion of open long bone fractures. External fixation, particularly the FESSA frame, is highly valued for its safety, ease of application, and convenience in soft tissue wound care. To evaluate the outcomes of treating open tibial shaft fractures using the FESSA external fixation system at Thong Nhat Hospital. A retrospective cross-sectional study was conducted on 53 patients with open tibial shaft fractures treated with the FESSA frame. Bone healing was assessed using the RUST scoring system, and functional recovery was evaluated using the Karlström-Olerud criteria. The bone union rate was 92.3%, with an average healing time of 6.75 ± 3.44 months. Good and excellent functional recovery outcomes accounted for 87.5%. The FESSA external fixation system is an effective method for managing open tibial shaft fractures.

Evaluation of the analgesic effect of low-power intravascular laser combined with electroacupuncture compared to electroacupuncture alone in patients with chronic low back pain treated at the Traditional Medicine Department of Thong Nhat Hospital. 60 patients with confirmed diagnosis of chronic back pain at the Department of Traditional Medicine, Thong Nhat Hospital. Patients were randomly divided into 2 groups. The control group (n=30) was treated with electroacupuncture; the intervention group (n=30) was treated with low-power intravascular laser combined with electroacupuncture similar to the control group. The treatment course was continuous for 10 days, once a day. Treatment effectiveness was assessed based on the VAS pain scale assessed after 5 and 10 days of treatment. After 10 days of treatment, the VAS pain score was 2,42 ± 1,67 in the control group and 1,57 ± 1,48 in the intervention group. Both groups experienced a reduction in pain to the levels of no pain (0–2 points) or mild pain (2–4 points). The intervention group demonstrated superior pain relief starting from day 5, reaching statistical significance by day 10 (p = 0.03 < 0.05). Combining electroacupuncture with intravascular low-level laser therapy  enhance effeciency in relive pain due to lumbago. No significant side effects were noted.

46 patients (patients) with proximal humerus fractures were operated on at Thong Nhat Hospital from January 2019 to April 2024. They were divided into 2 groups, group 1: 22 patients with the support of 3D printing models and group 2: 24 patients without 3D models. All patients were open reduction and internal fixation with a locking plate on the proximal humerus. The patients were evaluated for bone healing and deformity on X-ray, and shoulder function was assessed according to the Constant scale. Surgical time of group 1 (90.68 ± 13.029) was shorter than group 2 (105.25 ± 12.037). Mean blood loss of group 1 (164.55 ± 50.042) was less than group 2 (218.75 ± 28.789). Shoulder function were very good and good, accounting for a high rate of 82.6%, and there was no difference between the 2 groups. Postoperative complications had a low rate and there was no difference between the 2 groups in wound surface infection and subacromial conflict. Complications of screw perforation, osteomyelitis, and bone nonunion have not been observed.

To evaluate the clinical features, paraclinical findings, and treatment outcomes of giant cell tumor (GCT) of bone. Fifteen patients aged 20 to 40 years with bone lesions underwent surgery and histopathological examination and were diagnosed with “giant cell tumor of bone” between January 2011 and December 2024. There were 6 males and 9 females. The most common tumor location was the tibia (53.3%). The most frequent histological pattern was fibrosis, present in 11 cases (73.3%). The average follow-up duration was 55 months. Local recurrence occurred in 3 out of 15 cases, with no cases of metastasis. The GCT cases in our study shared pathological characteristics with classic GCT populations. No specific histological feature was associated with adverse outcomes. Curettage combined with bone cement filling proved to be an effective treatment option.

Non-variceal upper gastrointestinal bleeding (NVUGIB) is a common medical emergency requiring early risk stratification to improve prognosis. This study aimed to evaluate the value of the Glasgow-Blatchford Score (GBS) in prognosticating patients with NVUGIB. This prospective, descriptive study included patients diagnosed with NVUGIB admitted to the Emergency Department of Thong Nhat Hospital from January 2020 to July 2020. Among 122 patients (73.0% male, mean age 63 years), 45.9% required medical intervention (MI), 5.7% experienced re-bleeding, and 2.5% died. The mean GBS was 9. The GBS (AUC=0.828) showed better prognostic value for MI than the clinical Rockall score (AUC=0.650). With a cut-off score of ≥10, the GBS had a sensitivity of 0.68 and a specificity of 0.88 in predicting the need for MI. Most patients with NVUGIB were elderly. The GBS is a valuable tool for prognosticating the need for medical intervention in this patient group.